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Project Management

Location:
New York, NY
Posted:
June 24, 2014

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Resume:

Grace Chen

*** * **** ******, *** York, NY *****

Phone: 917-***-****, E-Mail: acepcl@r.postjobfree.com

QUALIFICATIONS AND SUMMARY

• Productive independent biological science researcher with publications in respected

journals

• Experience in managing research projects and collaborating with scientists from different

research fields

• Excellent communication skills and presented results at international conferences

EDUCATION

• Ph.D. Department of Immunology, University of Toronto, Toronto, ON, Canada 2002-2008

• B.Sc. (Honors), University of Toronto, Toronto, ON, Canada 1998-2002

RESEARCH/PROJECT MANAGEMENT EXPERIENCE

Postdoctoral Fellow, Albert Einstein College of Medicine, Bronx, NY, USA Nov 2010-present

Principal Investigator: Paul S. Frenette

• Initiated, managed and accomplished multiple research projects.

• Collaborated with physicians in an on-going clinical trial study.

Projects:

(1) Project planning: Formulated project proposal/timeline and

created a budget plan for a collaborative project with NKT Therapeutics Inc. last

year. Currently, setting up another collaborative project with GlaxoSmithKline

(GSK) Pharmaceuticals (project proposal writing and project budget planning)

(2) Current project: Role of iNKT cells in sickle cell disease

Collaborate with NKT Therapeutics Inc. on examining the role of iNKT cells in

sickle cell disease

(3) Role of β 2 integrin on neutrophils in sickle cell disease

pathogenesis

Examined the effect of β2 integrin deficiency on sickle cell disease progression

by examining aged β2 integrin-deficient humanized sickle cell mouse model

(4) Role of platelets in sickle cell disease pathogenesis

Uncovered the role of platelets in sickle cell disease vaso-occlusive crisis

using humanized sickle cell mouse model and fluorescent intravital microscopy

imaging of live animals

(5) Contribution of neutrophil extracellular traps to the

pathogenesis of sickle cell disease

Uncovered the role of neutrophil extracellular traps in sickle cell disease

complication acute chest syndrome using humanized sickle cell mouse model

(6) Treatment of sickle cell vaso-occlusive crisis with high dose

IVIG: A phase I/II study

Collaborated with physicians and analyzed blood samples of patients with

sickle cell disease pre- and post-IVIG treatment

Ph.D. Research, University of Toronto, Toronto, Ontario, Canada 2002-2008

Principal Investigator: Robert Rottapel

Dissertation Title: Functional analysis of adapter protein c-Abl Src

Grace Chen, CV Page 2

Homology 3 domain-binding protein 2

Uncover the function of adapter protein, 3BP2, in immune cells, B cells and

neutrophils

COMMUNICATION EXPERIENCE

Excellent writing skills

• Wrote and published three first author primary research papers and one review

article in international, peer-reviewed journals.

Excellent communicator

• Conference oral presentation: The American Society of Hematology (ASH) 55th 2013

Annual Meeting (Oral session “Hemoglobinopathies, excluding Thalassemia: Insight

Into the Pathophysiology of Sickle Cell Disease”) (New Orleans, Louisiana)

2008

• Thesis defense: Research presentation (open to the public); Examination

(restricted to examination committee) (Toronto, Ontario)

• Conference poster presentation: Cold Spring Harbor Conference titled 2007

“Phosphorylation, signaling and Disease” (Cold Spring Harbor, New York)

• Conference poster presentation: FASEB Summer Research Conference titled

2006

“Lymphocytes and Antibodies” (Indian Wells, California)

• Conference poster presentation: Annual Ogryzlo Research Day (Division of

Rheumatology, Department of Medicine, University of Toronto) (Toronto, Ontario) 2005

• Conference poster presentation: Keystone Symposia titled “Cellular Senescence

and Cell Death/Survival and Death in Immune Tolerance and Homeostasis”

2005

(Keystone, Colorado)

• Conference oral presentation: Annual Ogryzlo Research Day (Division of

Rheumatology, Department of Medicine, University of Toronto) (Toronto, Ontario) 2004

• Fluent in Mandarin Chinese

• Conversational ability in Japanese

PUBLICATIONS

• Chen, G., Zhang, D., Fuchs, T.A., Manwani, D., Wagner, D.D., Frenette, P.S.,

Blood. (2014), 123 (24): 3818-27

• Chen, G., Dimitriou, I., Milne, L., et al. J Immunol. (2012), 189 (5): 2138-50

• Dimitriou ID, Clemenza, L., Scotter, A.J., Chen, G., Guerra, F.M., Rottapel, R.,

Immunol Rev. (2008), 224: 265-83

• Chen, G., Dimitriou, I., La Rose, J., et al. Mol Cell Biol. (2007), 27(8): 3109-22

LEADERSHIP/MENTORING EXPERIENCE

Volunteer Mentor (International Student Center) 2009-2010

• Provide referral information about the University of Toronto procedures,

support services, resources, and extra-curricular activities on and off-campus

• Communicate with mentees in person on regular basis

• Attend mentor meetings and submit monthly mentor progress reports

Grace Chen, CV Page 2

AWARDS/FUNDING

• The American Society of Hematology (ASH) Abstract Achievement Award 2013

• David Rae Graduate Student Scholarship 2005-2006

• Dick and Peggy Sharp Graduate Student Fellowship in Immunology 2004-2005

• Ontario Graduate Scholarship in Science and Technology 2002-2006

• University of Toronto Open Fellowship Award (Entrance scholarship) 2002



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