Grace Chen
*** * **** ******, *** York, NY *****
Phone: 917-***-****, E-Mail: acepcl@r.postjobfree.com
QUALIFICATIONS AND SUMMARY
• Productive independent biological science researcher with publications in respected
journals
• Experience in managing research projects and collaborating with scientists from different
research fields
• Excellent communication skills and presented results at international conferences
EDUCATION
• Ph.D. Department of Immunology, University of Toronto, Toronto, ON, Canada 2002-2008
• B.Sc. (Honors), University of Toronto, Toronto, ON, Canada 1998-2002
RESEARCH/PROJECT MANAGEMENT EXPERIENCE
Postdoctoral Fellow, Albert Einstein College of Medicine, Bronx, NY, USA Nov 2010-present
Principal Investigator: Paul S. Frenette
• Initiated, managed and accomplished multiple research projects.
• Collaborated with physicians in an on-going clinical trial study.
Projects:
(1) Project planning: Formulated project proposal/timeline and
created a budget plan for a collaborative project with NKT Therapeutics Inc. last
year. Currently, setting up another collaborative project with GlaxoSmithKline
(GSK) Pharmaceuticals (project proposal writing and project budget planning)
(2) Current project: Role of iNKT cells in sickle cell disease
Collaborate with NKT Therapeutics Inc. on examining the role of iNKT cells in
sickle cell disease
(3) Role of β 2 integrin on neutrophils in sickle cell disease
pathogenesis
Examined the effect of β2 integrin deficiency on sickle cell disease progression
by examining aged β2 integrin-deficient humanized sickle cell mouse model
(4) Role of platelets in sickle cell disease pathogenesis
Uncovered the role of platelets in sickle cell disease vaso-occlusive crisis
using humanized sickle cell mouse model and fluorescent intravital microscopy
imaging of live animals
(5) Contribution of neutrophil extracellular traps to the
pathogenesis of sickle cell disease
Uncovered the role of neutrophil extracellular traps in sickle cell disease
complication acute chest syndrome using humanized sickle cell mouse model
(6) Treatment of sickle cell vaso-occlusive crisis with high dose
IVIG: A phase I/II study
Collaborated with physicians and analyzed blood samples of patients with
sickle cell disease pre- and post-IVIG treatment
Ph.D. Research, University of Toronto, Toronto, Ontario, Canada 2002-2008
Principal Investigator: Robert Rottapel
Dissertation Title: Functional analysis of adapter protein c-Abl Src
Grace Chen, CV Page 2
Homology 3 domain-binding protein 2
Uncover the function of adapter protein, 3BP2, in immune cells, B cells and
neutrophils
COMMUNICATION EXPERIENCE
Excellent writing skills
• Wrote and published three first author primary research papers and one review
article in international, peer-reviewed journals.
Excellent communicator
• Conference oral presentation: The American Society of Hematology (ASH) 55th 2013
Annual Meeting (Oral session “Hemoglobinopathies, excluding Thalassemia: Insight
Into the Pathophysiology of Sickle Cell Disease”) (New Orleans, Louisiana)
2008
• Thesis defense: Research presentation (open to the public); Examination
(restricted to examination committee) (Toronto, Ontario)
• Conference poster presentation: Cold Spring Harbor Conference titled 2007
“Phosphorylation, signaling and Disease” (Cold Spring Harbor, New York)
• Conference poster presentation: FASEB Summer Research Conference titled
2006
“Lymphocytes and Antibodies” (Indian Wells, California)
• Conference poster presentation: Annual Ogryzlo Research Day (Division of
Rheumatology, Department of Medicine, University of Toronto) (Toronto, Ontario) 2005
• Conference poster presentation: Keystone Symposia titled “Cellular Senescence
and Cell Death/Survival and Death in Immune Tolerance and Homeostasis”
2005
(Keystone, Colorado)
• Conference oral presentation: Annual Ogryzlo Research Day (Division of
Rheumatology, Department of Medicine, University of Toronto) (Toronto, Ontario) 2004
• Fluent in Mandarin Chinese
• Conversational ability in Japanese
PUBLICATIONS
• Chen, G., Zhang, D., Fuchs, T.A., Manwani, D., Wagner, D.D., Frenette, P.S.,
Blood. (2014), 123 (24): 3818-27
• Chen, G., Dimitriou, I., Milne, L., et al. J Immunol. (2012), 189 (5): 2138-50
• Dimitriou ID, Clemenza, L., Scotter, A.J., Chen, G., Guerra, F.M., Rottapel, R.,
Immunol Rev. (2008), 224: 265-83
• Chen, G., Dimitriou, I., La Rose, J., et al. Mol Cell Biol. (2007), 27(8): 3109-22
LEADERSHIP/MENTORING EXPERIENCE
Volunteer Mentor (International Student Center) 2009-2010
• Provide referral information about the University of Toronto procedures,
support services, resources, and extra-curricular activities on and off-campus
• Communicate with mentees in person on regular basis
• Attend mentor meetings and submit monthly mentor progress reports
Grace Chen, CV Page 2
AWARDS/FUNDING
• The American Society of Hematology (ASH) Abstract Achievement Award 2013
• David Rae Graduate Student Scholarship 2005-2006
• Dick and Peggy Sharp Graduate Student Fellowship in Immunology 2004-2005
• Ontario Graduate Scholarship in Science and Technology 2002-2006
• University of Toronto Open Fellowship Award (Entrance scholarship) 2002