RAJNANDANI KASHYAP

E-mail: aceo5g@r.postjobfree.com

Mobile:+91-994*******

CAREER OBJECTIVE

> To provide my endeavors in the research and corporate world with my

skills and knowledge that I posses for personal and organizational

growth.

> To deliver efficient and reliable solutions to critical situations

thereby adding value to the organization through my continuous

learning and innovation.

Area of Interest

> My Area of Interest includes Structural Biology including Protein

studies involving its purification and crystallization which involves

cell and molecular biology and basics of Recombinant DNA technology.

INTERNSHIPS/ EXPERIENCES

> National Centre for Biological Sciences,Bangalore (9 April 2014 -

Presently Working in Dr. Ranabir Das's lab):

Working on "Expression, purification and NMR study of Brca complex

protein PalB2 " under Dr. Ranabir Das, NCBS, Bangalore.

> Bhabha Atomic Research Centre, Mumbai (1 June 2013 to 2 August 2013):

Worked on "Expression, purification and crystallization of RecQ1

helicase" under Dr. Mukesh Kumar, Scientific officer (G), Solid state

physics division,Protein crystallography section.

> B. R. Nahata College of Pharmacy, Mandsaur [M.P.](1 June 2012 to 15 July

2012):

Got trained under Technology Information, Forecasting and Assessment

Council Centre of Relevance & Excellence in Green Pharmacy(TIFAC CORE)

Research Program (TCRP) in clinical research and BA/BE studies(2011-

2012) with enrollment number:2012/04.

During this tenure also got hands on training of the basic

instrumentation of Biotechnology and assisted a preclinical research

study entitled "Anti-arthritic activity of fenugreek on arthritic

rat".

> K. N. K. College of Horticulture, Mandsaur [M.P.](June 2011):

Learned the skills of tissue culture/micropropagation of Sandalwood

(Santalum album L.) under Dr. S. N. Mishra,Principal scientist, M &

AP, Project,College of Horticulture, Mandsaur [M.P.].

PROJECTS

> Minor Project: "Expression, purification and crystallization of RecQ1

helicase" in which Expression of human RecQ1 helicase was attempted in

bacterial host. It was found that the protein is getting over- expressed,

however, most of the protein goes in insoluble inclusion body. Various

attempts were made to bring maximum protein in soluble fraction by

lowering the temperature after induction, reducing the amount of IPTG,

changing the growth medium, etc. Best results were obtained when

temperature after induction was reduced to 15oC and 3% alcohol was added

to the growth medium. Small amount of protein was purified from the

soluble fraction, although the amount was not sufficient to carry out

crystallization trials. Efforts were also put in to extract the protein

from inclusion bodies.

If the crystals would have been produced then they would be used to

screen potent inhibitors which have been obtained in the laboratory

earlier from virtual screening of seven million of compounds. Thus to

study how these novel inhibitors are binding to the protein as it has

been found recently that inhibition of RecQ1 in cancer cells renders them

sensitive towards ionizing radiations while sparing the normal cells.

Thus it will have tremendous therapeutic implication, especially in case

of pancreatic cancer and will help mankind.

TECHNICAL PROFICIENCY

> Basic programming knowledge in languages: C, C++

> DSA, DBMS

ACHIEVEMENTS

> Awarded Indian academy of sciences fellowship 2013 for 2 months from 1

June to 2 August,2013 at Bhabha atomic research centre, Mumbai with

enrolment number as LFS2359 under Dr. Mukesh Kumar, Scientific officer

(G), Solid state physics division,Protein crystallography section, BARC,

Mumbai.

> Won first prize for poster in National symposium on "Urban Water

Management" with Title as "Artificial Ecosystem From Sewage Water" held

at Vivekananda Institute of Technology on 25th February 2012.

> Scholarship Holder in Amity University Rajasthan under the scheme of

"Merit cum means" (Year 2012-13).

> Secured 144th rank at Junior Level in National Level Biotechnology

Talent Search Examination, Online, Organized by Biotech Helpline

Foundation on 27th Feb, 2011.

> Participated in National Science Olympiad, 2010 and secured 1st Rank in

Mandsaur [M.P.] and 22nd Rank at State level [Madhya Pradesh]. Actively

participated in various debates during school sessions as well as held at

Interschool Level.

> Volunteer at "International conference on "Green Biotech: Recent Trends

and Innovations" at Amity University Rajasthan, Jaipur from November 12-

13, 2011.

> Certificate of Merit for performing in "CONNEXIONS" the intercultural

event organized by Amity School of Languages, Amity University Rajasthan

on 10 October, 2011.

PROFESSIONAL & SCHOLASTIC QUALIFICATIONS

Degree Institute/ Board Year Percentage

2014

B.Tech. Amity University (VII Semester) 89.4%

(Biotechnology) Rajasthan Class

Topper

Senior C.B.S.E. 78.6%

Secondary certificate St. Thomas Sr. Sec. 2010

School, Mandsaur [M.P.]

Secondary Certificate C.B.S.E. 2008 81.2%

St. Thomas Sr. Sec.

School, Mandsaur [M.P.]

PUBLICATIONS & CONFERENCES

1. Attended workshop on "Harnessing intellectual property and its

management for growth and prosperity" organized by National research

development corporation, New Delhi and Amity University Rajasthan, Jaipur

on 9 January,2014.

2. Participated in Poster Presentation on "Nano particles as efficient

carriers of Doxorubicin" in International Symposium on

Pharmacotherapeutics and Biomedical Approaches in Health and Diseases",

SOPICON 2012 at NIMS University, Jaipur on 23-25 November, 2012

.Published in Journal of Pharmacovigilance & Drug Safety, volume 9,number 4,Oct-Dec,2012 with ISSN 0972-8899 as P80.

3. Abstract published on " A new and innovative method to harvest water

hyacinth as a space biofuel" in Global Biofuels and Bioproducts Summit

organized by OMICS Group of Conferences at Texas, USA on 19-21 November,

2012 with reference id Rajnandani kashyap,J.Pet Environ Biotechnol

2012,3.7 available on open access link as http://dx.doi.org/10.4172/2157-

7463.S1.007.

4. Paper presented on "Application of Water Hyacinth as Space Biofuel" in

"National Conference on Emerging Trends in Renewable Energy Technology

(ETRET)-2012", at Uttam Devi Mohan Lal College of Engineering, Jaipur on

20-21 April, 2012.

5. Participated in Poster Presentation on "Artificial Ecosystem for Sewage

Water" in National Conference on New Methods and Technologies for Water

Conservation and Purification" at Poornima Group of Colleges, Jaipur on

3rd March, 2012.

6. Presented poster in National symposium on "Urban Water Management" with

Title as "Artificial Ecosystem From Sewage Water" held at Vivekananda

Institute of Technology on 25th February 2012.

7. Presented poster in "International conference on "Green Biotech: Recent

Trends and Innovations" at Amity University Rajasthan, Jaipur from

November 12-13, 2011.

PERSONAL DOSSIER

Father's Name Mr.R.N.Kashyap

Gender Female

Marital Status Unmarried

Nationality Indian

Email aceo5g@r.postjobfree.com

Mobile +91-994*******

Date of birth June, 17, 1992

Language proficiency English, Hindi, French

Address 22K, Laxman Temple, Kailash Marg,

Mandsaur, M.P.,

458001

REFERENCES

1. Dr. Ranbir Das, Principal Investigator,National Centre for Biological

Sciences,Bangalore.

Email: aceo5g@r.postjobfree.com

2. Dr. Mukesh Kumar, Scientific officer (G), Protein Crystallography

Section, Bhabha Atomic Research Centre, Mumbai, India.

E-mail: aceo5g@r.postjobfree.com

3. Dr. (Prof.) A.N. Pathak, Director of Amity Institute of Biotechnology,

Amity University Rajasthan (AUR), Jaipur, Rajasthan, India.

E-mail: aceo5g@r.postjobfree.com

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