Natalia Guggisberg, M.S., M.D.

e mail: ace2g1@r.postjobfree.com

phone: 901-***-****

Positions and Employment

****- **** ********* ********* ********* Fellow Translational Laboratories Tom

Baker Cancer Center, Alberta, Calgary

2010-11 University of Miami, Research Associate, Miami, Fl Project To Cure Paralysis

Confocal microscopy, cell culture,immunohistochemistry and clinical trials projects to

cure paralysis, behavioral analysis and statistical analysis of the data.

2009 Atlas Inc. Pharmaceutical company, Miami, Fl Quality assurance and Quality

control Scientist

02/2008- 06/2009 Postdoctoral Research Associate, Department of Biochemistry and

Molecular Biology, Braman Breast Cancer Institute, University of Miami, FL. Project:

RhoC expression in breast cancer. I successfully implemented ki 67, p27 expression

scoring system for xenograft tumor models. Techniques: immunohistochemistry, cell

culture, western blot, statistical analysis of the data. RSK1 Tumorogenesis study. P27

immunohistochemistry scoring project. Successfully completed immunohistochemistry

analysis for the Faslodex and AZD0530 study, in press Clinical Cancer Research

07/2006-07/2007 Blood Bank Transfusion Medicine Fellow, Medical College of

Georgia, Augusta, GA. Responsibilities: teaching medical students, fellows and medical

technologists rotating at the blood bank. Lectures and presentations for the faculty and

residents at the clinical pathology conferences. Evidence- based lectures for the medical

residents and staff. Communicating with clinicians and medical doctors regarding

transfusion related issues of the patients. Rhogam issues investigations. Quality control

and quality assurance.

07/2002-07/2006 Pathology Resident, University of Tennessee, Memphis TN.

Described gross features of specimens, dissected surgical specimens: colon,

breast,lung,liver,spleen,kidneys,skin and ensured appropriate tissue submission for

histologic examination. I have also worked for LabCorp grossing all the gastrointestinal

and skin surgical biopsies. Performed autopsies and postmortem examinations

Photographed selected gross specimens for conferences or documentation

Assisted in the conduct of quality control/assurance within the department

Interacted effectively with laboratory staff, pathologists, and others

Performed miscellaneous job duties as assigned by the Pathologist

Assisted in the conduct of quality control/assurance within the department

08/2001-07/2002 Senior Research Technologist, Department of Otolaryngology,

Medical College of Wisconsin. Project: Middle ear epithelial mucin production in

response to interleukin-6 exposure in vitro. Techniques: molecular biology techniques,

PCR, in situ hybridization, Southern blot, immunohistochemistry, cell culture, SPSS,

statistical data analysis.

08/1999-08/2001 Research Assistant, University of Wisconsin-Milwaukee. Project:

Low dose radiation exposure and risk of cancer. Managing the research project on the

environmental effects on human health, statistical analysis of the data using SPSS and

Excel packages.

1998 Research Assistant, Marquette University, Neuroscience Laboratory. Project:

Periventricular nucleus response to stress in rodents. Techniques: PCR, in situ

hybridization, histochemistry, DNA, RNA, agarose gel electrophoresis; protein isolation.

EDUCATION

02/200*-**-**** Postdoctoral Research Associate, Department of Biochemistry and

Molecular Biology, Braman Breast Cancer Institute, University of Miami, FL.

2007/06-07/2007 Blood Bank Transfusion Medicine Fellow, Medical College of

Georgia, Augusta, GA.

07/2002-07/2006 Pathology Resident, University of Tennessee, Memphis, TN.

08/1999-08/2001 M.S., Clinical Laboratory Sciences, University of Wisconsin-

Milwaukee, WI.

07/1988-07/1994 M.D., Novosibirsk Medical Institute.

CERTIFICATION

1998 ECFMG Certificate

2006 Certificate of completion of the residency training in Pathology

2007 Certificate of completion of transfusion medicine and blood banking fellowship

program

HONORS and AWARDS

1992 Dean’s List, Novosibirsk Medical Institute

2000 Graduate scholarship award in Clinical Laboratory Sciences, University of

Wisconsin-Milwaukee

2008 Doris Duke Breast Cancer Fellowship Award

2012 Canadian Cancer Society Junior Investigator Grant Panel Award

MEMBERSHIPS

2002- present College of American Pathology

2002- present American Society for Clinical Pathology

2002- present Tennessee Medical Association

2006- present Southern Medical Association

2011- present American Association for Cancer Research

PUBLICATIONS

Guggisberg, N., Bollag, R., and Cook, L., Cold Agglutinin disease, American Society for

Clinical Pathology. Transfusion Medicine Vol 52, 2009.

Chen, Y.,Guggisberg N., Jorda, M., Slingerland, J. Combined Src and aromatase

inhibition impairs human breast cancer growth in vivo and bypass pathways are activated

in AZD0530 resistant tumors, Clinical Cancer Research, Clin Cancer Res. 2009 May

15;15.

Chen, Y., Alvarez, E., Azzam, D., Wander S., Guggisberg, N., Jorda M., Slingerland, J.

Combined Src and ER Blockade Impairs Human Breast Cancer Proliferation In Vitro and

In vivo. Breast Cancer Res Treat. 2010 Jul 29.

Kornaga, E.N., Klimowicz, A.C., Konno M., Guggisberg, N., Ogilvie T., Magliocco, T.,

Morris, D. Comparison of three commercial ER/PR assays on a single clinical outcome

series. Abstract number 851594, 2012 CTRC-AACR San Antonio Breast Cancer

Symposium.

Evaluation of RT qPCR and Luminex Based Methodolgies in HER2 Breast Cancer Testing

2014 CTRC-AACR San Antonio Breast Cancer Symposium.

PRESENTATIONS

01/2013 Comparison of three commercial ER/PR assays on a single clinical outcome,

Tom Baker Cancer Center

04/2009 Aromatase inhibitors and their antitumor effects, University of Miami.

01/2007 Evidence Based medicine series, Medical College of Georgia.

03/2007 Current guidelines for fresh frozen plasma usage, Medical College of Georgia

01/2007 Current usage of intravenous immune globulin, Medical College of Georgia.

02/2007 Thrombotic Thrombocytopenic Purpura, Malaria, Medical College of Georgia

08/2005 Malaria, University of Tennessee

INVITED SPEAKER

11/25/2011 Pathologist View on EGFR Mutation Testing, Boehringer Ingelheim

(Canada ) LTD. Western Canada Advisory Board Meeting

TEACHING EXPERIENCE

2006-2007 Teaching medical technologists, students, and medical Residents during their

Blood Bank Rotation at the Medical College of Georgia, Augusta, GA

2002-2006 Presentations in Clinical Pathology to the medical residents, dental students,

and medical technologists, University of Tennessee-Memphis.

1998-2001 Substitute Teacher, South Milwaukee School District, Milwaukee, WI

SKILLS

Ability to analyze epidemiological data using epidemiological techniques

Ability to analyze the data using statistical software (EXCEL, SPSS)

Excellent skills in presenting the data at meetings and conferences

Ability to conduct research leading to scientific publication

Excellent ability to apply organizational, communication, and educational skills to

various audiences and settings

Ability to determine the appropriate methods and design study instruments to collect data

Knowledge of molecular biology techniques and clinical epidemiology methods

VOLUNTEER

2013 Bust a move, Alberta Cancer Foundation

2011 Tom Baker Cancer Center Alberta Calgary 30th Anniversary Celebration

2010 Southside Elementary School, Miami, FL

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