Julia Schauer

*** ********* **** *********

Coatesville, Pennsylvania

19320

Insightful, results-driven pharmaceutical / biotech laboratory professional with proven

610-***-****

success directing and conducting a broad range of protein purification and

acdq6p@r.postjobfree.com

characterization techniques is seeking a challenging position in research and/or

product development.

Qualifications

Excel at managing complex projects, understanding advanced scientific concepts and

conducting sound experiments to synthesize new information. Effective manager of

time and resources. Sixteen years of extensive laboratory experience in monoclonal

antibody modification, purification and characterization, protein and peptide chemistry,

molecular biology and biochemical techniques, cell culture, in-vitro and in-vivo study

design and analysis, organic synthetic chemistry, analytical chemistry, radiochemistry,

plasmid DNA complex formation, assay development, formulations, and laboratory

safety in a cGMP environment. My experience also includes laboratory- based data

generation and interpretation, coordination of in-house and outside collaborations,

technical group presentations, patent support, written reports, and publication of

manuscripts in several professional journals.

“Julia has demonstrated herself to be an excellent communicator and to have the

ability to effectively supervise situations and personnel in a matrix structure. We need

more employees like this.”

Dr. Richard Carrano, Vice President, Technology Devmt. and Regulatory Affairs

1994 Performance Review Excerpt, Apollon, Inc.

Work Experience

Self Employed Artist

8/2008 - present

Educator: Chemistry and Physics

8/2002 - 8/2008 Downingtown Area School District, Downingtown, PA

Senior Research Scientist

11/1992 - 8/2000 Wyeth Ayerst Research (formerly Apollon, Inc.), Malvern, PA

Prepared and purified modified proteins, antibodies, and antibody fragments. As the

point person in collaboration with the Molecular Hepatology Dept. of Harvard Medical

School, I prepared conjugated IgG antibodies utilizing my own bifunctional ligands.

The resulting antibody conjugates were complexed with DNA and tested for receptor

targeted cellular uptake in-vitro.

Promoted to lead the DNA-based vaccine delivery program. Invented and

developed novel strategies to transfect cells with plasmid DNA. Collaborated with

medical, scientific and legal professionals, including M.D.'s, Ph.D.'s and patent

attorneys. Identified goals and priorities in support of deadline-driven objectives.

Directed junior staff, executed and documented research experiments, and reported

results in technical group presentations and in published peer-reviewed manuscripts.

Conducted cell culture experiments utilizing sterile technique to screen product

candidates for efficacy in-vitro. Independently optimized the assay and identified the

lead compound.

Conducted the total synthesis of a variety of molecules including carbohydrates,

steroids, peptides, polyamines, chelating agents, modified proteins, and receptor

targeted DNA transfection agents.

Prepared and utilized radioactive probes for elucidating DNA complexation

mechanisms.

Conducted stability studies and physico-chemical characterization of DNA

complexes including dynamic light scattering, zeta potential determination, and sizing

by flow cytometry.

Senior Research Associate

6/1987 - 11/1992 Centocor, Inc., Malvern, PA

Developed and optimized purification and characterization methods for radio-labeled

monoclonal antibodies and antibody fragments, and also for complex organic

compounds. Conducted biochemical analyses (SDS-PAGE, Size Exclusion HPLC,

and IEF) of monoclonal antibodies. Conducted biochemical analyses (ELISA,

Western blots, RIA) of both human patient (blood serum) and laboratory samples to

evaluate efficacy of various monoclonal antibody based drug products. Prepared and

tested radioactive imaging agents as new diagnostic products for cancer and heart

disease. Supervised scale up preparation of a new product for use in several human

clinical trials.

Junior Research Chemist

7/1984 - 8/1986 Johnson Matthey, Inc., West Chester, PA

Synthesized organic molecules to attach platinum to monoclonal antibodies as new

chemotherapeutic drugs.

Education

8/2000 - 5/2002 West Chester University/ M. Ed. Chemistry, West Chester, PA

Master's Degree

Cumulative GPA: 3.9 / 4.0

1/1981 - 5/1984 West Chester University/ B.S. Chemistry, West Chester, PA

Bachelor's Degree

Cumulative GPA: 3.8 / 4.0, Summa cum Laude Honors graduate.

Skills

Cell and molecular biology techniques and assay development, HPLC, FTIR, UV-Vis,

SDS-Page electrophoresis, particle size analysis, gel filtration, radio-immuno and

ELISA assay development, elemental analysis, mass spectrometry, gas

chromatography, atomic absorption, NMR, sterile technique, formulations, protein

purification, thin layer chromatography, GLP and GMP, laboratory safety, MS Office

(Word, Excel, PowerPoint, etc.), excellent verbal and written communication skills.

Additional Information

Six years of additional experience as a professional science educator have advanced

my interpersonal, time management and presentation skills. I work well with individuals

of diverse backgrounds, and maintain a professional demeanor in stressful situations.

References available upon request

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