Jose Rodriguez

**** ******* ***** **** *******, TX77049 713-***-**** acdq68@r.postjobfree.com

LABORATORY SUPERVISOR

Highly focused, result driven laboratory supervisor with extensive background in medical mycology research.

Experienced scientific liaison who demonstrates practical research on the bench and on murine models.

Offers advance computer skills in MS Office Suite, highly organized, efficient and skilled in a variety of

laboratory support including:

Key Skills

Laboratory Management Spreadsheet & Database Creation Records Management

Teambuilding & Supervision Image Collection & Analysis Inventory Management

Staff Development & Training Quality Control/Quality Assurance Fungal Identifications and Testing

Policies & Procedures Manuals Proficiency Testing Bilingual Spanish

Maintain CLIA/CAP accreditations

Experience

UNIVERSITY of TEXAS HEALTH SCIENCE CENTER, Houston, TX 1997 to Present

Lab Supervisor

Support the Director of the Laboratory of Mycology Research, in the Department of Internal Medicine, Division

of Infectious Diseases for the University of Texas Medical School at Houston.

My areas of expertise include: antifungal susceptibility testing, fungal serologies, PK of antifungals, in vivo murine

models of mycoses and clinical trials in prophylaxis and treatment of fungal infections.

Plan and coordinate all hands on in vivo and in vitro research, i.e. Beta Glucan tests, drug prep/dosing animal

models

and data collections, Instructor for rotating Infectious Disease Fellows as well as Lab Instructor for the Latin

American Antibiotic Resistance Workshops. Perform and oversee all unknown yeast identification and

susceptibility

research. Also maintains an accredited CLIA and CAP laboratory on a quarterly basis.

HARRIS COUNTY HOSPITAL DISTRICT, Houston, TX 1993 to 1997

Patient Care Technician

Responsible for taking the patient’s medical history, vital signs, phlebotomy, and assisting physician’s during

examinations.

Education

University of Phoenix, Houston, TX 2011

Associate of Arts in Healthcare Administration

Channelview High School, Channelview, TX 1992

High School Diploma

Certificates

Center for Laboratory Animal Medicine and Care (CLAMC)

• Intro to Laboratory Animal Science

• Practical Research Methodology (Rodents)

NIH Web based Research Training

• HIPPA and Human Subject Research

UCLA

• HIPPA Training Course

• Biomedical & Genetics Research

UTHSC

HIPPA/SSN Training Course

•

UTHSC Environmental Health and Safety

Universal Precautions

•

Exposure Control Plan

•

Safe Work Practices

•

Employee Exposure Evaluation

•

Engineering Controls

•

Personal Protection Equipment

•

Hazard Communication

•

Emergency Response

•

Waste Disposal

•

UTHSC Fire Extinguisher Training

UTHSC Shipping Infectious & Biological Substances

UTHSC Blood borne Pathogens Training Course

Harris County Hospital District (HCHD)

Eye Chart Testing (visual acuity)

•

Electrocardiogram

•

CPR

•

Wound Management

•

Phlebotomy

•

PUBLICATIONS

Abstracts

Lozano Chiu M, Paetznick, VL, Rodriguez JR, Rex JH. Anit Candida Activity of the Sordarin

1.

Derivatives GW471552, GW471558, GW506540, GW531920, and GW560849: Effect of Endpoint Rule

and Incubation Time on MIC. 40th Interscience Conference on Antimicrobial Agents and Chemotherapy,

Submitted Abstract, 2000.

2. Ostrosky Zeichner L, Paetznick VL, Rodriguez JR, Chen E, Rex JH. In Vitro Antifungal Susceptibilities

of Trichosporon Species, abstr. 935. In Program and abstracts of 40 th Interscience Conference on

Antimicrobial Agents and Chemotherapy, Toronto, Canada, 2000.

3. Ostrosky Zeichner L, Paetznick VL, Mohr J, Rodriguez JR, Chen E, Sancak B, Rex JH. In Vitro

Antifungal Activity of FK 463 against Candida spp, abstr. 197. In Program and abstracts of 40 th

Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Canada, 2000.

4. Ostrosky Zeichner L, Bazemore SA, Paetznick VL, Rodriguez JR, Chen E, Wallace TL, Rex JH.

Antifungal Activity of Isomeric Forms of Nystatin (NYS), abstr. 1956.In Program and abstracts of 40 th

Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Canada, 2000.

5. Ostrosky Zeichner L, Paetznick VL, Sancak B, Rodriguez JR, Chen E, Rex JH. Correlation of minimum

inhibitory concentrations (MIC) and disk diffusion diameters (DDID) for FK 463 in 403 bloodstream

isolates of Candida spp., abstr J 572. In Program and abstracts of the 41st Interscience Conference on

Antimicrobial Agents and Chemotherapy, Chicago, USA, 2001.

6. Paphitou NI, Paetznick VL, Ostrosky Zeichner L, Rodriguez JR, Chen E, Rex JH. In vitro activity of

investigational triazoles against Trichosporon spp., abstr. J 814. In Program and abstracts of the 41st

Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, USA, 2001.

7. Paphitou NI, Paetznick VL, Ostrosky Zeichner L, Rodriguez JR, Chen E, Rex JH. In Vitro Activity of

Investigational Triazoles against Fusarium: Effects of Inoculum size, and Time of Reading on Broth

Microdilution Susceptibility Test Results, abstr. J 573. In Program and abstracts of the 41st Interscience

Conference on Antimicrobial Agents and Chemotherapy, Chicago, USA, 2001.

8. Andrade R, Ostrosky Zeichner L, Paetznick V, Rodriguez J, Chen E, Dudley M, Rex JH. Synergistic

Antifungal Effect of Fluconazole (FLU) and CDR1/2 Efflux Pump Inhibitors: Insights into the Trailing

Growth Phenomenon, abstr. M 223. In Program and abstracts of the 42 nd Interscience Conference on

Antimicrobial Agents and Chemotherapy, San Diego, USA, 2002.

9. Matar M, Ostrosky Zeichner L, Paetznick VL, Rodriguez JR, Chen E, and Rex JH. Correlation between

Etest (ET), Disk diffusion (DD) and Microdilution (MD) Methods for Antifungal Susceptibility Testing of

Fluconazole (FLU) and Voriconazole (VOR), abstr. M 1495. In Program and abstracts of the 42 nd

Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, USA, 2002.

10. Ostrosky Zeichner L, Matar M, Paetznick VL, Rodriguez JR, Chen E, and Rex JH. In Vitro Synergy

Testing of Anidulafungin (AFG) and Micafungin (MFG) in Combination with Amphotericin B (AMB)

Against Aspergillus spp. and Fusarium spp., abstr. M 1816 In Program and abstracts of the 42 nd

Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, USA, 2002.

11. Odabasi Z, Paetznick VL, Rodriguez JR, Chen E, McGinnis MR, Ostrosky Zeichner L. Differences in

Beta glucan (BG) levels in culture supernatants of a variety of fungi. Abstr. M 1021. 43 rd Interscience

Conference on Antimicrobial Agents and Chemotherapy, Chicago, 2003.

12. Ostrosky Zeichner L, Philip A, Odabasi Z, Paetznick VL, Rodriguez JR, chen E, Rex JH. Comparison of

Colony Forming Unit (CFU) Counts and Quantitative PCR (qPCR) Conidial Equivalent (CE)

Measurement in a Murine Model of Fusariosis. Abstr. M 362. 43rd Interscience Conference on

Antimicrobial Agents and Chemotherapy, Chicago, 2003.

13. Ostrosky Zeichner L, Mohr J, Finkel KW, Rodriguez JR, Rex JH. Pharmacokinetics and safety evaluation

of IV itraconazole/cyclodextrin (IV ITR) in stable hemodialysis (HD) patients. Abstr. M 2056. 43 rd

Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, 2003.

14. Philip A, Odabasi Z, Rodriguez JR, Paetznick VL, Chen E, Ostrosky Zeichner L, Rex JH. In Vitro

Synergy Testing of Anidulafungin (ANID) with Itraconazole (ITR) and Voriconazole (VOR) against

Aspergillus spp. and Fusarium spp. Abstr. M 988. 43rd Interscience Conference on Antimicrobial Agents

and Chemotherapy, Chicago, 2003.

15. Odabasi Z, Paetznick VL, Rodriguez JR, Chen E, Ostrosky Zeichner L. Pilot Survey of Anidulafungin

(ANI) Against Selected Mould Isolates. 9th Congress of the European Confederation of Medical Mycology

and 7th Trends in Invasive Fungal Infections. Abstr. O3.05. Amsterdam, The Netherlands, 2003.

16. Ostrosky Zeichner L, Rex JH, Paetznick VL, Rodriguez JR, Chen E, Pappas PG, Dismukes WE. Lack of

Correlation of In Vitro Checkerboard Based Antifungal Combination Results with Clinical Outcomes.

Abstr. M 1679. 44th Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington DC,

2004.

17. Sims CR, Paetznick VL, Rodriguez JR, Chen E, Ostrosky Zeichner L. Correlation between Microdilution

(MD), E test (ET) and Disk Diffusion (DD) Methods for Antifungal Susceptibility Testing of

Posaconazole. Abstr 24. Focus on Fungal Infections 15, Miami, USA, 2005.

18. Mohr JF, Paetznick V, Rodriguez J, Finkelman M, Cocanour CS, Rex JH, Ostrosky Zeichner L. A

Prospective Pilot Survey of B glucan Seropositivity and Its Relationship to Invasive Candidiasis in the

Surgical ICU. Abstract #M 168. 45th Interscience Conference on Antimicrobial Agents and

Chemotherapy. Washington DC, 2005.

19. Sims CR, Paetznick VL, Rodriguez JR, Chen E, Ostrosky Zeichner L. Contemporary Treatment and

Outcomes of Zygomycosis in a Non Oncological Tertiary Care Center. Abstract #273. 43rd Annual

Meeting of the Infectious Diseases Society of America. San Francisco CA, 2005.

20. Sims CR, Ostrosky Zeichner L, Paetznick VL, Rodriguez J, Chen E. Comparison of Abelcet and

Voriconazole Alone and in Combination in a Murine Model of Fusariosis Using Survival and Organ

Clearance by TaqMAn qPCR. Abstract P049. Focus on Fungal Infections 16, Las vegas, NV, USA, 2006.

21. Sims CR, Mohr J, Paetznick V, Rodriguez J, Finkelman M, Ostrosky Zeichner L. Correlation of Clinical

Outcomes with β Glucan (BG) Levels in Patients with Invasive Candidiasis (IC). Abstract #M 1599. 46th

Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco CA, 2006.

22. Mattiuzzi G, Kantarjian H, Odabasi Z, Alvarado G, Cassat J, Paetznick V, Rodriguez J, Chen E,

Ostrosky Zeichner L. Diagnostic Performance of Serum Galactomannan (GM) and Beta Glucan (BG) in a

Cohort of 395 Patients (pts) with Acute Leukemia on Antifungal Prophylaxis (AP). Abstract M 578. 47th

Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, 2007.

23. Ostrosky Zeichner L, Paetznick VL, Rodriguez J, Chen E, Sheehan DJ. Activity of Anidulafungin (AFG)

in a Murine Model of Candida krusei Infection: Evaluation of Mortality and Disease Burden by

Quantitative Tissue Cultures and Serum Beta Glucan (BG) Levels. Abstract M 1840. 47th Interscience

Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, 2007.

24. Ostrosky Zeichner L, Paetznick VL, Rodriguez J, Chen E, Kartsonis NA, Douglas C. Activity of

Caspofungin (CFG) Alone and in Combination with Amphotericin B Lipid Complex (ABLC) in a Murine

Model of Fusariosis. Abstract M 1841. 47th Interscience Conference on Antimicrobial Agents and

Chemotherapy. Chicago, IL, 2007.

25. Ostrosky Zeichner L, Mattiuzzi G, Xiao L, Kantarjian H, Rodriguez J, Chen E, Paetznick V. Preliminary

report of a possible association of voriconazole with false positive (1, 3) b D glucan (BG): Important

implications for diagnosis, therapeutic monitoring, and research. Abstract #27. Focus on Fungal Infections

18, San Antonio, TX, USA, 2008.

26. Ostrosky Zeichner L, Inurria N, Rodriguez J, Chen E, Paetznick V. Comparative In Vitro Activity of

Isavuconazole (ISA) against Medically Important Yeasts and Moulds. Abstract M 1707. 49th Interscience

Conference on Antimicrobial Agents and Chemotherapy, San Francisco, California, 2009.

27. Krishnan S, Kruzel M, Wanger A, Chen E, Rodriguez J, Paetznick V, Ostrosky Zeichner L.

Contemporary Epidemiology of Candidemia (CA) in a Tertiary Care Center: Insights into Molecular

Epidemiology. Abstract M 1012. 49th Interscience Conference on Antimicrobial Agents and

Chemotherapy, San Francisco, California, 2009.

28. Krishnan S, Mattiuzzi G, Cortes J, Rodriguez J, Ostrosky Zeichner L. M 417 Kinetics of (1,3) Beta D

Glucan (BG) in Patients with Hematologic Malignancies Receiving Voriconazole (VOR) Prophylaxis.

Abstract M 417. 50th Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston,

Massachusetts, 2010.

Original Articles

1. Ostrosky Zeichner L, Bazemore S, Paetznick VL, Rodriguez JR, Chen E, Wallace T, Cossum P, Rex JH.

Differential Antifungal Activity of Isomeric Forms of Nystatin. Antimicrob Agents Chemother 2001;

45:2781 6

2. Paphitou NI, Ostrosky Zeichner L, Paetznick VL, Rodriguez JR, Chen E, Rex JH. In Vitro Antifungal

Susceptibilities of Trichosporon spp. Antimicrob Agents Chemother 2002; 46:1144 6.

3. Paphitou NI, Ostrosky Zeichner L, Paetznick VL, Rodriguez JR, Chen E, Rex JH. In Vitro Activities of

Investigational Triazoles against Fusarium Species: Effects of Inoculum Size and Incubation Time on

Broth Microdilution Susceptibility Test Results. Antimicrob Agents Chemother 2002; 46:3298–300.

4. Matar MJ, Ostrosky Zeichner L, Paetznick VL, Rodriguez JR, Chen E, Rex JH. Correlation between E

test, Disk diffusion, and Microdilution Methods for Antifungal Susceptibility Testing of Fluconazole and

Voriconazole. Antimicrob Agents Chemother 2003; 47:1647 51.

5. Odabasi Z, Paetznick VL, Rodriguez JR, Chen E, Ostrosky Zeichner L. In Vitro Antifungal Activity of

Anidulafungin Against Selected Clinically Important Mould Isolates. Antimicrob Agents Chemother

2004; 48:1912 5.

6. Mohr JF, Finkel KW, Rex JH, Rodriguez JR, Leitz GJ, Ostrosky Zeichner L. Pharmacokinetics of

Intravenous Itraconazole in Stable Hemodialysis Patients. Antimicrob Agents Chemother 2004; 48:3151

3.

7. Philip A, Odabasi Z, Rodriguez J, Paetznick VL, Chen E, Rex JH, Ostrosky Zeichner L. In Vitro Synergy

Testing of Anidulafungin with Itraconazole, Voriconazole, and Amphotericin B against Aspergillus spp.

and Fusarium spp. Antimicrob Agents Chemother 2005;49:3572 4.

8. Odabasi Z, Paetznick VL, Rodriguez JR, Chen E, McGinnis MR, Ostrosky Zeichner L. Differences in

beta glucan levels in culture supernatants of a variety of fungi. Med Mycol. 2006;44:267 72.

9. Sims CR, Paetznick VL, Rodriguez JR, Chen E, Ostrosky Zeichner L. Correlation between

Microdilution, E test, and Disk Diffusion Methods for Antifungal Susceptibility Testing of Posaconazole

against Candida spp. J Clin Microbiol 2006;44:2105 8.

10. Ostrosky Zeichner L, Paetznick VL, Rodriguez J, Chen E, Sheehan DJ. Activity of anidulafungin in a

murine model of Candida krusei infection: Evaluation of mortality and disease burden by quantitative

tissue cultures and serum (1,3) ß D glucan levels. Antimicrob Agents Chemother 2009; 53:1639 41.

11. Odabasi Z, Paetznick VL, Rodriguez JR, Chen E, Rex JH, Leitz GJ, Ostrosky Zeichner L. Lack of

correlation of 24 vs. 48 h itraconazole minimum inhibitory concentrations with microbiological and

survival outcomes in a guinea pig model of disseminated candidiasis. Mycoses 2010; 53:438 422.

12. Mohr JF, Sims C, Paetznick V, Rodriguez J, Finkelman MA, Rex JH, Ostrosky Zeichner L. A Prospective

Survey of (1 >3) ß D glucan and its Relationship to Invasive Candidiasis in the Surgical ICU Setting. J

Clin Microbiol. 2011; 49:58 61.

13. Chaturvedi V, Ramani R, Andes D, Diekema DJ, Pfaller MA, Ghannoum MA, Knapp C, Lockhart SR,

Ostrosky Zeichner L, Walsh TJ, Marchillo K, Messer S, Welshenbaugh AR, Bastulli C, Iqbal N, Paetznick

VL, Rodriguez J, Sein T. Multi laboratory Testing of Two Drug Combinations of Antifungals against

Candida albicans, Candida glabrata, and Candida parapsilosis. Antimicrob Agents Chemother. 201;

55:1543 8.

14. Sims CR, Jaijakul S, Mohr J, Rodriguez JR, Finkelman Malcolm, Ostrosky Zeichner L. Correlation of

Clinical Outcomes with ß Glucan Levels in Patients with Invasive Candidiasis. J. Clin Microbiol 2012,

50(6):2104 2106.

Contact this candidate