JEREMY GRIFFIN, PhD

*** ********* ***** • Hamden, CT 06514

Telephone: 860-***-****

E-mail: acayag@r.postjobfree.com

SUMMARY Goal oriented individual with strong industry, academic, and leadership experience within the

medical device and biotechnology field. Seeking opportunities to apply technical proficiencies

and intuition to help develop and market medical devices and/or technologies.

RELEVANT Covidien; North Haven, CT 06/2009 – Present

EXPERIENCE Senior Development Engineer 01/2013 – Present

Cross-functional involvement in the development and implementation of a Wound Closure and

Biosurgery product portfolio to meet emerging customer needs. Collaborate with many internal

and external sources to identify and support technical and clinical findings.

Senior Development Scientist 11/2011 – 01/2013

Developed and maintained a strong Research and Development technology pipeline to align with

the strategic goals of the Soft Tissue Implant division. Tasks included initiating work on project

concepts by providing technical and clinical product research information as relevant, to

determine the ability of Covidien to meet customer needs through current or advanced

technology, products, and services. Identified, created, and maintained key external

relationships to refine and identify attributes for new research activities. Relationships included

KOLs (surgical and technological), surgeons, external technology, and specialist consultants as

needed.

- Development of two product concepts included: 1) local analgesic delivery from a soft

tissue implant, and 2) a unique ventral hernia mesh implant with a synthetic film anti-

adhesion barrier. Formulation progression involved lab-scale production to preclinical

model study development and execution.

Research and Development Industrial Post-Doctoral Fellow 01/2011 – 11/2011

Established dynamic relationships with surgeons and KOLs to optimize design efforts for clinical

prototypes of novel soft tissue repair implants. Communicated clinical findings to the technical

team responsible for advancing the platform through the product development process.

Research and Development Industrial Co-op 05/2010 – 01/2011

Developed combination soft tissue implants; more specifically, coatings/films/microparticles.

Built prototypes and conducted general experimentation in support of medical device new

product development. Designed, executed, and documented formulation development and

analytical/mechanical testing.

- Preclinical development of novel localized drug delivery technologies to replace systemic

administration and inconvenient local delivery devices

Rutgers University; New Brunswick, NJ 01/2007 – 12/2010

Department of Biomedical Engineering PhD Thesis

Optimized and developed drug-releasing polymeric guidance tubes for nerve regeneration

following traumatic injury, under the direction of Dr. Kathryn Uhrich. The biodegradable polymer

scaffolds have the advantage of transitioning neurons from the injured state to the healthy

state, while avoiding permanent implants or nerve grafting.

- Development of novel polymer-drug implants to synergistically repair peripheral nerve

lesions and mitigate local wound inflammation

Covidien; North Haven, CT 06/2009 – 08/2009

Research and Development Graduate Intern

Worked intimately with the engineering staff within the Research and Development department

to fabricate and characterize soft tissue biomedical devices with controlled active therapeutic

delivery capabilities.

JEREMY GRIFFIN PAGE 2

Boston Scientific; Marlborough, MA 01/2006 – 08/2006

Research and Development Intern

Performed testing, validation, and documentation of an embolic microsphere medical device as a

research and development intern within the Oncology department of a major medical device

research and manufacturing company.

Worcester Polytechnic Institute; Worcester, MA 08/2005 – 05/2006

Senior Major Qualifying Project

Member of a four person research group characterizing the viscoelastic properties of

polyacrylamide gels for cell culture methods with the four techniques of atomic force

microscopy, rheometry, automated ball indentation, and uniaxial testing. Quantifying the

properties of various concentrations of polyacrylamide allowed researchers to examine the

mechanical responses of specific cell types in a medium closely mimicking the mechanical

elasticity of the cells native tissue.

Drexel University; Philadelphia, PA 06/2005 – 08/2005

Research Experience for Undergraduates (REU)

Participated in the REU program under the leadership of Dr. Anthony Lowman. Performed

research involving innovative hydrogels in the Biomaterials and Drug Delivery laboratory of the

Chemical Engineering Department. The research involved tailoring injectable thermosensitive

hydrogels, three dimensional hydrated polymer networks, for the application of enhancing the

interior nucleus of dehydrated discs in the human spine. This novel biomaterial disc nucleus

replacement has the potential to replace the two current surgical procedures of disc disease

discectomy and disc fusion.

EDUCATION Doctor of Philosophy, Biomedical Engineering January 2011

Rutgers, The State University of New Jersey, New Brunswick, NJ

Bachelor of Science, Biomedical Engineering May 2006

Worcester Polytechnic Institute, Worcester, MA

PUBLICATIONS Ouimet, M.A., Griffin, J., Carbone-Howell, A.L., Wu, W.H., Stebbins, N.D., Di, R., and Uhrich,

K.E. (2013) “Biodegradable Ferulic Acid-containing Poly(anhydride-ester): Degradation products

with controlled release and sustained antioxidant activity,” Biomacromolecules; 14(3): 854-861.

Witherell, R., Ebersole, G., Lord, D., Griffin, J., Sargeant, T., Beers, D., Strichartz, G., Stopek,

J., Elachchabi, A., Broom, D. (2012) “The preclinical technical feasibility of providing

postoperative analgesia by formulation of a sustained release bupivacaine-eluting hernia repair

textile,” Anesthesia and Analgesia; under review.

Rosario-Meléndez, R., Griffin, J., Bodnar, J., Halperin, F., Harper, I., Lavelle, L., Uhrich, K.E.

(2011) “Stability of a salicylate-based poly(anhydride-ester) to electron beam and gamma

radiation,” Polymer Degradation and Stability; 96(2011): 1625-1630.

Griffin, J., Delgado, R., Meiners, S., Uhrich, K.E. (2011) “Salicylic acid-derived poly(anhydride-

ester) electrospun fibers designed for regenerating the peripheral nervous system,” Journal of

Biomedical Materials Research, Part A; 97A(3): 230-242.

Delgado-Rivera, R., Griffin, J., Ricupero, C.L., Grumet, M., Meiners, S., Uhrich, K.E. (2010)

“Microscale plasma-initiated patterning of electrospun polymer scaffolds,” Colloids and Surfaces

B: Biointerfaces; 84(2): 591-596.

Griffin, J., Carbone, A., Delgado, R., Meiners, S., Uhrich, K.E. (2009) “Design and evaluation of

novel polyanhydride blends as nerve guidance conduits,” Acta Biomaterialia; 6(6): 1917-1924.

JEREMY GRIFFIN PAGE 3

Prudencio, A., Carbone, A. L., Griffin, J., Uhrich, K.E. (2009) “A novel approach for

incorporation of mono-functional bioactive phenols into polyanhydrides,” Macromolecular Rapid

Communication; 30 (13): 1101-1108.

Schmeltzer, R. C., Johnson, M., Griffin, J., Uhrich, K.E. (2008) “Comparison of salicylate-based

poly(anhydride-esters) formed via melt-condensation vs. solution polymerization,” Journal of

Biomaterials Science Polymer Edition; 19(10): 1295-1306. [invited]

PATENTS Griffin, J., Elachchabi, A., Broom, D., Witherell, R., Ebersole, G., Stopek, J. (2013) ‘Implantable

Porous Device Including a Film,” Patent disclosure.

Griffin, J., Elachchabi, A., Stopek, J. (2010) “Compositions and methods for preparing drug

eluting films directly from emulsifier/steric stabilizing polymers used for microparticle synthesis,”

Patent disclosure.

Uhrich, K.E., Buettner, H.M., Ezra, M., Griffin, J., Kohn, J., Schachner, M., Shreiber, D.I., Song,

M., Irintchev, A. (2009) “Nerve Guidance Tubes,” Patent disclosure (under review).

PRESENTATIONS Bodnar, S., Griffin, J., Gua, L., Halperin, F., Harmon, A.M., Harper, I., Langowski, B.A.,

Lavelle, L. Rosario-Meléndez, R., Sparks, S.M., Uhrich, K.E. (2010) “Impact of ionizing radiation

on the physiochemical properties of novel polymer therapeutics,” Abstract for American

Chemical Society Boston Conference.

Hehir, S., Plourde, N. Griffin, J., Moghe, P.V., Uhrich, K.E. (2010) “Design and synthesis of

nanoscale amphiphilic macromolecules with optimal binding properties to human scavenger-

receptor A: An investigation into the influence of stereochemistry and conformation,” Abstract

for American Chemical Society Boston Conference.

Greenwald, A., Griffin, J., Uhrich, K.E. (2009) “Establishment of microscale biomolecular

gradients for use in peripheral neuron regeneration,” Undergraduate Research Symposium,

Department of Chemistry and Chemical Biology, Rutgers University.

deRonde, B., Carbone, A., Griffin, J., Uhrich, K.E. (2009) “ Synthesis and characterization of

xylene-based copolymers for peripheral nerve regeneration,” Undergraduate Research

Symposium, Department of Chemistry and Chemical Biology, Rutgers University.

Griffin, J., Carbone, A., Delgado, R., Meiners, S., Uhrich, K.E. (2009) “Fabrication and

evaluation of bioactive-based polyanhydride nerve guidance conduits,” Abstract for “Polymers in

Tissue Engineering” NJ ACS Polymer Topical Group Symposium, New Brunswick, NJ.

Griffin, J., Carbone, A., Delgado, R., Meiners, S., Uhrich, K.E. (2009) “Fabrication and

evaluation of bioactive-based polyanhydride nerve guidance conduits,” Abstract for Biomedical

Engineering Society Annual Fall Meeting, Pittsburgh, PA.

Griffin, J., Delgado, R., Meiners, S., Uhrich, K.E. (2008) “In vitro evaluation of µ-scale plasma-

initiated patterned poly(anhydride-ester) and 3D nanofibrillar substrates,” Abstract for The New

Jersey Center for Biomaterials: 9th Symposium Biomaterials Science.

Griffin, J., Delgado, R., Meiners, S., Uhrich, K.E. (2008) “In vitro evaluation of µ-scale plasma-

initiated patterned biodegradable polymers and 3D nanofibrillar substrates,” Abstract for

American Chemical Society Philadelphia Conference [Macromolecular Assemblies for

Biomolecules, Cells and Tissues].

Griffin, J., Song, M., Carbone, A., Uhrich, K.E. (2007) “In vitro dorsal root ganglia viability in a

mimetic nerve guidance conduit environment,” Abstract for American Chemical Society Boston

Conference.

JEREMY GRIFFIN PAGE 4

RELEVANT Chemistry: Organic Chemistry of High Polymers, Biochemistry, polymer synthesis, and polymer

characterization (1H-NMR spectroscopy, thermal gravimetric analyzer, differential scanning

SKILLS &

EXPERIENCES calorimetry, goniometer, UV-VIS spectroscopy, HPLC)

Biology: Cell Molecular Biology, Experimental Physiology for Engineers, fluorescent microscopy,

aseptic cell culture technique, primary neuronal cell culture (rat), and small animal surgery (rat

sciatic nerve isolation)

Engineering: Transport Phenomena, Kinetic Thermodynamics and Transport, Experimental

Biomechanics, Biofluids, Image J®, mechanical analysis (Bose Enduratec Elf 3200, MTS Q/Test 5,

Dynamic Mechanical Analyzer, Instron, rheometry), SEM, and electrospinning

Leadership/Management: Marketing Management, International Business, Organizational

Behavior, Business Communications, patent and grant/proposal writing, project leadership, and

mentor for undergraduate students/interns

MENTOREES Joanna Marczyk, (Covidien Summer 2013)

Michael Arena, Intern (Covidien Summer 2012)

Kiersten Giusto, Biochemistry Intern (Covidien Summer 2011)

Andrew Greenwald, Microbiology and Biochemistry major (Rutgers Fall 2008-Spring 2010)

Natasha Piracha, Neurobiology major (Rutgers Spring 2007-Spring 2009)

Daniel Mints, Biomedical Engineering major (Rutgers Fall 2007-Spring 2008)

Jorge Rodriguez, Biomedical Engineering major (Rutgers Fall 2007- Spring 2008)

HONORS & DFSS Green Belt (2013 training completed and certification in progress)

ACTIVITIES National Science Foundation K-12 Graduate Student Teaching Fellow (2008-2009)

CeMBR Graduate Fellowship (2007-2008)

Johnson & Johnson Graduate Fellowship (2006-2007)

American Chemical Society (2007 – Present)

Research Experience for Undergraduates Drexel University (2005)

Tau Beta Pi National Engineering Honor Society (2004 – Present)

Charles O. Thompson Scholar (2003)

District I Verizon Academic All-American (2003)

Biomedical Engineering Society (2002 – Present)

WPI Varsity Football (2002 – 2005)

REFERENCES Available upon request

WEBSITE www.linkedin.com/in/jeremygriffin1

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