Manager Health

Location:

Bend, OR

Posted:

February 10, 2013

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Resume:

Generally Recognized As Safe . . .

What is GRAS Status?

Why the Butterfly?

***** ********* **** 541-***-****

Bend, OR 97702-3074 abqjg3@r.postjobfree.com

www.gras-associates.com

Richard A. Davis, Ph.D., DABT

Biography

Rick Davis

has over 25 years of experience in product safety, occupational health

and regulatory affairs for the chemical, agricultural and

pharmaceutical industries. He was certified in general toxicology and

has been a Diplomate of The American Board of Toxicology since 1980,

their charter year. His principal areas of expertise include safety

evaluation and risk assessment. His primary goal has been to develop

the means to permit the safe and effective use of products. He also

served as a member and was a key contributor to the activities of

several industry trade associations, including The European Crop

Protection Association Toxicology Expert Group, The Chemical Industry

Council/New Jersey Risk Assessment Task Force, The Formaldehyde

Institute, and The Ethylene Oxide Industry Council, among others. He

also holds an appointment as Adjunct Associate Professor and teaches

online in the Toxicology Program at the University of Medicine &

Dentistry of New Jersey, School of Health Related Professions.

FDA Experience

Testing and registration of pesticides, animal drugs and other indirect food additivesThreshold of Regulation exemption for substances in contact with foodSafety testing and evaluation of pharmaceuticals and over-the-counter drug productsToxicology and safety pharmacology reviews for pharmaceutical IND and NDA submissionsRisk assessment of pharmaceutical degradation products and impurities

Resume

1999

- 2006 Associate Professor and Faculty Member (part-time) -

Toxicology Program -

Department of Clinical Laboratory Sciences -

School of Health Related

Professions University of Medicine &

Dentistry of New Jersey, Newark, NJ

1994

- 1999 Senior Product Registration Manager - American Cyanamid

Company - Agricultural Products Research Division - International

Regulatory Affairs,

Princeton, NJ

1992

- 1994 Program Manager - American Cyanamid Company - Cyanamid

Agricultural

Research Center - Toxicology Department, Princeton, NJ

1989

- 1992 Manager, Toxicology Operations - American Cyanamid Company -

Chemicals

Group Toxicology and Product Safety Department, Wayne, NJ

1983

- 1989 Toxicology Program Manager - American Cyanamid Company -

Chemicals Group -

Toxicology and Product Safety Department, Wayne, NJ

1979 - 1983 Staff Toxicologist - Celanese Corporation - Department of Environmental,

Health and Safety Affairs, New York, NY

1975

- 1979 Division Pharmacologist / Physiologist - U. S. Air Force -

6570th Aerospace Medical Research Laboratory -Toxic Hazards Division,

Wright-Patterson Air Force Base, OH

Adjunct

Associate Professor - Pharmaceutical and Product Safety Evaluation

Professionals Track - Master of Science in Health Sciences Program -

University of Medicine & Dentistry of New Jersey - School of Health

Related Professions - Department of Clinical Laboratory Sciences, 2006

- PresentAdjunct Faculty

Member and Lecturer - Georgian Court College - Graduate School of Arts

and Sciences - Department of Biology, 2003 - 2005Adjunct

Assistant Professor, Toxicology Program - University of Medicine &

Dentistry of New Jersey - School of Health Related Professions -

Department of Clinical Laboratory Sciences, 1993 - 1999

Committee Assignments & Positions

1993 - 1994 - Chemical Industry Council/New Jersey - Risk Assessment Task Force

1992

- 2004 - Thesis Advisory Committees - UMDNJ - New Jersey Medical School

- Graduate School of Biomedical Sciences - Department of Pharmacology

and Toxicology "The Interaction of Paraoxon with Human Recombinant Acetylcholinesterase", Clint Rosenfeld, B.S., July 14, 2004 "Studies on the Hepatotoxicity of Flunitrazepam and Alcohol in Combination", Mahmoud Assaf, M.S., 1998 "Pharmacokinetics and Pharmacodynamics of Benzophenone-3 in the Rat", Chukwuemeka S. Okereke, Ph.D., 1994"Functional and Pharmacokinetic Studies on the Interaction of Aspirin

and Salicylamide in Rats", Maged M. Rizk, M.D., Ph.D., 1992

1992

- 1994 - American Cyanamid Company - Agricultural Research Division -

Institutional Animal

Care and Use Committee - Corporate Occupational

Health Committee

1990 - 1992 - New Jersey Hazardous Substances Management Research Center - Health Effects

Assessment Division, Advisory Board

1989 - 1991 - The Formaldehyde Institute - Board of Directors Chairman, Science and Health

Committee

1981 - 1982 - Chemical Manufactures Association - Toxic Substances Control Act Testing

Committee

Professional Memberships

Davis,

Richard, Michael Dourson, Bette Meek, Margaret Miller, Jay Murray,

Bruce Naumann and Edward Ohanian. A National and International Debate

on Default Uncertainty Factors vs. Data-Derived Uncertainty Factors.

Human and Ecological Risk Assessment, 8(4), 895-911, 2002.Kadry,

Abdelrazak M., Chukwuemeka S. Okereke, Mohamed S. Abdel-Rahman,

Marvin A. Friedman, and Richard A. Davis. "Pharmacokinetics of

Benzophenone-3 After Oral Exposure in Male Rats." Journal of Applied

Toxicology, 15 (2), 97-102, 1995.Okereke,

Chukwuemeka S., Abdelrazak M. Kadry, Hosni Hosni, Mohamed S.

Abdel-Rahman, Richard A. Davis, and Marvin A. Friedman. "Metabolism of

Benzophenone-3 in Rats." Drug Metabolism and Disposition, 21 (5):

788-791, 1993.Grammer, Leslie

C., Martha A. Shaughnessy, Richard A. Davis and Roy Patterson.

"Exposure to TMXDI (meta) Aliphatic Isocyanate and TMI (meta)

Unsaturated Aliphatic Isocyanate." Journal of Occupational Medicine,

35 (3): 287-290, 1993.Daston,

G.P., S.D. Gettings, B.D. Carlton, M. Chudkowski, R.A. Davis, A.L.

Kraus, C.F. Luke, R.E. Quellette, T.A. Re, A.M. Hoberman and C.P.

Sambuco. "Assessment of the Reproductive Toxic Potential of Dermally

Applied 2-Hydroxy-4-Methoxybenzophenone to Male B6C3F1 Mice."

Fundamental and Applied Toxicology, 20 (1): 120-124, 1993.Davis,

Richard A. "The Assessment of Safe Formaldehyde Occupational Exposure

Limits." Comments on Toxicology, 4 (4): 331-347, 1992.Davis, Richard A. "Current Issues in Formaldehyde: An Overview." Comments on Toxicology, 4 (4): 265-267, 1992.Abdel-Nabi,

Ismail M., Addelrazak M. Kadry, Richard A. Davis and Mohamed S.

Abdel-Rahman. "Development and Validation of a High-Performance Liquid

Chromatographic Method for the Determination of Benzophenone-3 in

Rates." Journal of Applied Toxicology 12 (4): 255-259, 1992.Davis, Richard A. "Toxicology of Powder Coating Crosslinkers." Modern Paint and Coatings, pp 44-45, April 1992.Goodrich,

Mark S., Mark J. Melancon, Richard A. Davis and John J. Lech. "The

Toxicity, Bioaccumulation, Metabolism, and Elimination of Dioctyl

Sodium Sulfosuccinate DSS in Rainbow Trout (Oncorhynchus Mykiss)."

Water Research, 25 (2): 119-124, 1991.Pereira,

M.A., M.M. Khoury, H.P. Glauert and R.A. Davis. "Screen of Five Alkyl

Carbamates for Initiating and Promoting Activity in Rat Liver." Cancer

Letters, 57: 37-44, 1991.Vernon,

Patricia A. and Richard A. Davis. "Acute Toxicologic Evaluation of

m-TMXDI/TMP Adduct." Acute Toxicity Data 1 (2): 106-107, 1990.Vernon, Patricia A. and Richard A. Davis. "Acute Toxicologic Evaluation of MAGME." Acute Toxicity Data 1 (1): 46-47, 1990.Vernon, Patricia A. and Richard A. Davis. "Acute Toxicologic Evaluation of m-TMXDI." Acute Toxicity Data 1 (1): 45-46, 1990.Vernon, Patricia A. and Richard A. Davis. "Acute Toxicologic Evaluation of meta-DIPEB." 1(1): 44-45, 1990.Vernon, Patricia A. and Richard A. Davis. "Acute Toxicologic Evaluation of meta-TMI." Acute Toxicity Data 1 (1): 43-44, 1990.Miller,

G.A., R.A. Davis, and J.C. Caporossi. "Toxic Gas Replacements For

Semiconductor Processing." Semiconductor Safety Association Journal 4

(3): 7-11, 1990.Mackenzie,

K., S. Henwood, G. Foster, F. Akin, R. Davis, P. DeBaeke, G. Sisson and

G. McKinney. "Three-Generation Reproduction Study with Dioctyl Sodium

Sulfosuccinate (DSS) in Rats." Fundamental and Applied Toxicology,

15:53-62, 1990.Davis, R.A.,

C.T. Olson, R.N. Terpolilli and K.C. Back. "Acute Toxicity Studies of

Triaminoguanidine Nitrate." Proceedings of the JANNAF Interagency

Propulsion Committee, 1978.Davis,

R.A., C.T. Olson, R.N. Terpolilli and K.C. Back. "Toxicity Studies of

Triaminoguanidine Nitrate." AMRL Report No. AMRL-TR-77-16, 1977.Davis,

Richard A., Ralph N. Terpolilli and Kenneth C. Back. "Toxic Point

Determination of Selected Hazardous Materials." Dept. of

Transportation Report No. DOT/MTB/OHMO - 75/4, 1975.

Monographs, Chapters & Book ReviewsDavis, Richard A. Book Review: "Toxicology and Regulatory Process". International Journal of Toxicology 25, 541-543, 2006.Davis,

Richard A. "Aliphatic Nitro, Nitrate and Nitrite Compounds," Chapter

10 in Patty's Industrial Hygiene and Toxicology, Fourth Edition, Volume

2, Part A, G.D. Clayton and F.E. Clayton eds., John Wiley and Sons,

Inc., 1993.Davis, Richard A. "Studies on Emetine Cardiotoxicity in Guinea Pigs." Ph.D. Dissertation, The Ohio State University, 1975.

Abstracts & PresentationsFord,

R., R. Davis and D. Gardner. "Development of Inhalation Thresholds of

Concern for the Evaluation of Tobacco Additives" The Toxicologist, 90

(1): #2317, 2006.Davis,

Richard A. Uncertainty Factor Accuracy: Data-Derived Factors are

Better Than Default Factors A National and International Debate on

Default Uncertainty Factors vs. Data-Derived Uncertainty Factors, 5th

Annual Conference on 10X Uncertainty Factors. University of Medicine

and Dentistry of New Jersey, Newark New Jersey. June 1, 2001.Okereke,

C.S., A.M. Kadry, M.S. Abdel-Rahman, R.A. Davis, and M.A. Friedman.

"Species Differences in Disposition of Benzophenone-3 After Oral

Administration in Male Rat and Mouse." The Toxicologist, 13 (1): 286,

1993.Kadry, A.M., H. Hosni,

C.S. Okereke, M.S. Abdel-Rahman, R.A. Davis and M.A. Friedman.

"Pharmacokinetics of Benzophenone-3 in Rats." The Pharmacologist 34

(3): 182, 1992.Okereke, C.S.,

H. Hosni, A.M. Kadry, M.S. Abdel-Rahman, R.A. Davis and M.A. Friedman.

"Metabolism of Benzophenone-3 in Rats." The Pharmacologist 34 (3):

179, 1992.Grammer, L.D., M.A.

Schaughnessy, R.A. Davis and R. Patterson. "Clinical and Immunologic

Evaluation of 95 Workers Exposed to Meta-Tetramethylene Xylene

Diisocyanate (TMXDI) and Dimethyl-M-Isopropenyl Benzyl Isocyanate

(TMI)." Journal of Allergy and Clinical Immunology 87 (1, Part 2),

#245, 1991.Davis, R.A., T.M.

Federici and M.A. Friedman. "A Dermal Carcinogenicity Study of

MAGME -100 Monomer." The Toxicologist 11 (1): 333, 1991Burleigh-Flayer,

H.D., D.E. Dodd, M.A. Friedman and R.A. Davis. "The Effects of

Meta-Tetramethylene Diisocyanate (m-TMXDI) Vapor on Respiratory Rate

and Tidal Volume of Swiss Webster Mice and Sprague-Dawley Rats." The

Toxicologist 10 (1): 205, 1990.Davis,

R.A., H.D. Burleigh-Flayer, D.E. Dodd and M.A. Friedman. "A 90-Day

Inhalation Toxicity Study of m-TMXDI (Meta-Tetramethylene Diisocyanate)

in Mice and Rats." The Toxicologist 10 (1): 204, 1990.Pereira,

M.A., H.P. Glauert, M.M. Khoury, P. Barnwell, M. Hensley and R.A.

Davis. "Test of Alkyl Carbamates for Tumor Initiation and for Tumor

Promotion in Rat Liver." The Toxicologist 9(1): 214, 1989.Ouelette,

R.E., C.S. Auletta and R.A. Davis. "Closed-Patch Repeated Insult

Dermal Sensitization Study in Guinea Pigs with Glyoxal." The

Toxicologist 9 (1): 242, 1989.Davis, R.A. and M.A. Friedman. "A Canine 90-Day Gavage Study of MAGME -100 Monomer." The Toxicologist 9 (1): 198, 1989.Mackenzie,

K., S. Henwood, G. Foster, F. Akin, R. Davis, P. DeBaeke, G. Sisson and

G. McKinney." Three-Generation Reproduction Study with Dioctyl Sodium

Sulfosuccinate (DSS) in Rats." The Toxicologist 7 (1): 176, 1987.Rodwell,

D.E., R.A. Davis, E.J. Tasker and M. A. Friedman. "A Fertility and

General Reproductive Performance Study in Rats with a Teratology Phase

on Diethylene Glycol." The Toxicologist 7(1): 145, 1987.Davis,

Richard A., and Marvin A. Friedman. "m-TMXDI: An Isocyanate Which

Does Not Cause Pulmonary Sensitization in Guinea Pigs." The

Pharmacologist 28 (3): 178, 1986.Davis,

R.A., J.C. Siglin, P.J. Becci, M.A. Friedman. "Acute Toxic Effects of

Acrylic Monomers on the Rat Forestomach with Gavage Administration."

The Toxicologist 6 (1): 188, 1986.Davis,

R.A., J.C. Siglin, P.J. Becci, M.A. Friedman. "Concentration

Dependence and Reversibility of Gastric Lesions Induced By Repeated

Gavage of Acrylic Monomers." The Toxicologist 6 (1): 188, 1986.Davis,

R.A., C.S. Auletta, and M.A. Friedman. "Isocyanate Dose-Related Dermal

Irritation and Delayed Contact Hypersensitization in Guinea Pigs." The

Toxicologist 5 (1): 251, 1985.Koshchier,

F.J., M.A. Friedman, R.A. Davis, and R. Gay. "Rabbit Alveolar

Macrophage (RAM) Cytotoxicity Assay Performed on Metal Coated Graphite

Fibers." The Toxicologist 4 (1): 2, 1984.Davis,

R.A., C.S. Auletta, G.M. Benke and J.J. Clary. "Tripropylene Glycol

Diacrylate (TRPGDA) Toxicity with Repeated Dermal Exposure." The

Toxicologist 3 (1): 152,1983.Davis,

R.A., M.E. George, K.C. Back. "Muscimol Antagonizes Methyhydrazine

Induced Convulsions." Toxicology and Applied Pharmacology 48 (1):

A197, 1979.Terpolilli, R.N.,

R.A. Davis, K.C. Back. "A Comparative Study of the Effects of Three

Halogenated Methanes on Cardiovascular Dynamics and Myocardial Energy

Metabolism." Toxicology and Applied Pharmacology 48 (1): A22, 1979.Terpolilli,

R.N., R.A. Davis, G.R. Peterson and K.C. Back. "The Effects of

Bromochlorodifluoromethane (BCF) on Contractility and Cardiac Tissue

Levels of High Energy Metabolites." Toxicology and Applied

Pharmacology 45 (1): 336, 1978.Davis,

R.A., and K.C. Back. "The Effects of Bromochlorodifluoromethane (BCF)

and MN++ on Rate Dependent Changes in Contractility of Isolated Atria."

Toxicology and Applied Pharmacology 45 (1): 227, 1978.Davis,

R.A., J.O. Lindower and P.B. Hollander. "Uptake, Subcellular

Distribution and Toxicity of 3H-Emetine During Chronic

Administration." Federation Proceedings 33 (3 Part I): 1656, 1974.Davis,

R.A. and P.B. Hollander. "Subcellular Distribution of Emetine-3H in

Isolated Perfused Guinea-Pig Heart." The Pharmacologist 15 (2): #329,

1973.Hollander, P.B., R.A.

Davis, and B.H. Marks. "Influence of Extracellular Potassium

Concentrations on Ouabain-Induced Changes of Transmembrane Potential

and Contractile Characteristics." The Pharmacologist 13 (2): #40,

1971.Davis, Richard and Philip

B. Hollander. "Alteration of Transmembrane Potential Configuration

Coincident with Glycoside-Induced Cardiac Arrhythmia." The

Pharmacologist 13 (2): #42, 1971.

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