CURRICULUM VITAE

James Tilford Elder, M.D., Ph.D.

Kirk D. Wuepper Professor of Molecular Genetic Dermatology

University of Michigan Department of Dermatology

and Comprehensive Cancer Center

7412 Medical Sciences I

1301 East Catherine

Ann Arbor, MI 48109-5675

Phone: 734-***-****

Fax: 734-***-****

E-mail: abp9ek@r.postjobfree.com

EDUCATION

9/1966-6/1970 Southwest High School, Kansas City, Missouri

9/1970-6/1974 Northwestern University, Evanston, Illinois; B.S.

(Biomedical Engineering with highest distinction)

9/1974-6/1981 Yale University School of Medicine, New Haven,

Connecticut; M.D. (Medical Scientist Training Program)

9/1974-6/1982 The Graduate School of Yale University; Ph.D. (Molecular

Biophysics and Biochemistry)

POSTDOCTORAL TRAINING

6/1981-6/1982 Postdoctoral Fellow, Department of Chemistry, University

of California at Berkeley

7/1982-6/1983 Intern in Internal Medicine, University of Washington

School of Medicine at Seattle

7/1983-7/1986 Senior Fellow in Dermatology, University of Washington

at Seattle

8/1986-6/1988 Senior Research Fellow in Dermatology, University of

Michigan

ACADEMIC APPOINTMENTS

1988-1994 Assistant Professor, Department of Dermatology, University of

Michigan

1988- Physician, Department of Dermatology, Veterans Administration,

Ann Arbor, MI, and Toledo, OH

1992-1994 Assistant Professor, Department of Radiation Oncology, Division

of Cancer Biology, University of Michigan

1994-2002 Associate Professor, Department of Dermatology, University of

Michigan

1994-2002 Associate Professor, Department of Radiation Oncology, Division

of Cancer Biology, University of Michigan

2002-2008 Professor, Department of Radiation Oncology, Division of Cancer

Biology, University of Michigan

1994 Member, Graduate Program in Cellular & Molecular Biology,

University of Michigan

1994- Member, Center for Molecular Medicine and Genetics, University

of Michigan

2002- Professor, Department of Dermatology, University of Michigan

James T. Elder, M.D., Ph.D. 4/14/11 1

2008 Kirk D. Wuepper Professor of Molecular Genetic Dermatology,

University of Michigan

CONSULTING POSITIONS

1993-1998 Oklahoma Center for the Advancement of Science and Technology

Oklahoma Health Research Program (continuation grant review)

1999-2002 Medical Advisory Board, National Psoriasis Foundation

2006- Committee on Scientific Programs, Society for Investigative

Dermatology,

2008- Scientific Advisory Committee, Lupus Family Registry and

Repository

2009- Scientific Advisory Committee, National Psoriasis Foundation

SCIENTIFIC ACTIVITIES

Editorial Boards

1987 Laboratory Investigation, Reviewer

1989- Journal of Investigative Dermatology, Reviewer

1989- Journal of Cellular Physiology, Reviewer

1990- Archives of Dermatology, Reviewer

1991- Experimental Dermatology, Advisory Board until 2007

1992- American Journal of Pathology, Reviewer

1992- Molecular and Cellular Biology, Reviewer

1992- British Journal of Cancer, Reviewer

1992- Journal of Clinical Investigation, Reviewer

1993- British Journal of Dermatology, Reviewer

1993- Cancer, Reviewer

1994- Skin Pharmacology, Reviewer

1994- Archives of Dermatological Research, Reviewer

1994- Proceedings of the National Academy of Sciences, Reviewer

1994- Genomics, Reviewer

1994- Cancer Research, Reviewer

1995- Blood, Reviewer

1996- Journal of Dermatologic Science, Reviewer

1997- American Journal of Human Genetics, Reviewer

1998- Differentiation, Reviewer

1998- Clinical Cancer Research, Reviewer

1999- Clinical and Experimental Dermatology, Editorial Board

2000- Biochimica Biophysica Acta, Reviewer

2000- Neoplasia, Reviewer

2000- Science, Reviewer

2001- Dermatology, Reviewer

2001- FASEB Journal, Reviewer

2001- Nature Medicine, Reviewer

2001- Cancer Biomarkers, Epidemiology, and Prevention, Reviewer

2002- International Journal of Dermatology, Reviewer

2002- Journal of Rheumatology, Reviewer

2002- Journal of Investigative Dermatology, Associate Editor

2002- Endocrine Reviews, Reviewer

2002- Physiological Genomics, Reviewer

2003- Archives of Dermatological Research, U.S. Editor

2003- Journal of Clinical Immunology, Reviewer

2003- Journal of Cell Science, Reviewer

2003- Human Molecular Genetics, Reviewer

2003- Journal of Medical Genetics, Reviewer

James T. Elder, M.D., Ph.D. 4/14/11 2

2005- Human Genetics, Reviewer

2005- Molecular Pharmacology, Reviewer

2005 Nature Genetics, Reviewer

2006 Nature, Reviewer

2006 Clinical and Experimental Dermatology, Reviewer

2006 Journal of the American Academy of Dermatology, Reviewer

2006 Genes and Immunity, Reviewer

2007 PLOS Biology, Reviewer

2009 Trends in Immunology, Reviewer

2009 American Journal of Physiology, Reviewer

2010 Science Translational Medicine, Reviewer

Study Sections

1992 National Institute of Arthritis and Musculoskeletal and Skin

Diseases, Skin Disease Research Centers

1993-95 Oklahoma Center for the Advancement of Science and Technology

Oklahoma Health Research Program Peer Review Panel

1994- General Clinical Research Center, University of Michigan,

Reviewer.

1995 National Institutes of Health, General Medicine A-2 Study Section.

1995-98 Dermatology Foundation, Medical and Scientific Committee

1996 National Institute of Health Division of Research Grants, Scientific

Review & Information Systems, ZRG4 (OBM-1)

1995-2001 Society for Investigative Dermatology, Committee on Scientific

Programs, Reviewer

1998 National Institutes of Health Division of Research Grants,

Scientific Review & Information Systems, ZRG1-OBM-1 (02),

Clinical Sciences Special Review Panel.

1999 Wellcome Trust, Biological Collections Committee, reviewer.

1999 National Institutes of Health Division of Research Grants,

Scientific Review & Information Systems, ZRG1-OBM-1 (01),

Clinical Sciences Special Emphasis Panel.

1999 National Institutes of Health Center for Scientific Review,

Scientific Review & Information Systems, ZRG-GMA-1 (3B)

Small Business Innovation Research Special Emphasis Panel

2000 National Institutes of Health Center for Scientific Review,

Scientific Review & Information Systems, ZRG-GMA-1 (01)

Small Business Innovation Research Special Emphasis Panel

2000 National Institute of Arthritis and Musculoskeletal and Skin

Diseases Special Emphasis Panel 2001/01 Council ZAR1 AAA-A

(J3), Skin Disease Research Centers

2001 National Institutes of Health Center for Scientific Review,

Scientific Review & Information Systems, 2001/05 Council ZRG-

GMA-1

2001 National Institutes of Health Center for Scientific Review,

Scientific Review & Information Systems 2001/05 Council ZRG1

GMA-1 (10) Small Business Innovation Research Special

Emphasis Panel

2001 Wellcome Trust, London, UK, Reviewer

2001 Michigan Diabetes Research and Training Center, Reviewer

2001 National Institute of Health Center for Scientific Review,

Scientific Review & Information Systems 2002/01 Council ZRG1

GMA-101 (10B) Small Business Innovation Research Special

Emphasis Panel

James T. Elder, M.D., Ph.D. 4/14/11 3

2002 National Institute of Arthritis, Musculoskeletal and Skin Diseases

Loan Repayment Program Evaluation Panel, Reviewer

2002 National Institute of Arthritis, Musculoskeletal and Skin Diseases

Special Emphasis Panel ZAR1 TAS-D O3 1, Individual

Postdoctoral Fellowships in Epidemiology / Clinical Research /

Outcomes Research in Skin Diseases

2003 National Institutes of Health Center for Scientific Review, Special

Emphasis Panel ZRG1-OBM-2-03

2003 National Institutes of Health Center for Scientific Review, Special

Emphasis Panel 2003/10 Council ZRG1-ALY-01-1

2004 National Institutes of Health Center for Scientific Review, Special

Emphasis Panel 2004/6 Council ZRG1-ACTS 01Q

2004 National Institutes of Health Center for Scientific Review, Special

Emphasis Panel ZRG1-MOSS-C 12

2004 National Institutes of Health Center for Scientific Review, Special

Emphasis Panel 2004/10 Council ZRG1-ACTS 01Q

2004 National Institutes of Health Center for Scientific Review, Special

Emphasis Panel ZRG1-MOSS-D 12

2004 VA Merit Review, Immunology B Study Section, Spring 2004

2004 VA Merit Review, Immunology B Study Section, Fall 2004

2005- Society for Investigative Dermatology, Committee on Scientific

Programs, Reviewer

2005 Texas A&M University, Center for Environmental and Rural

Health Pilot Project Program, ad hoc reviewer

2005 National Psoriasis Foundation Fellowship Selection Committee,

Reviewer

2006 VA Merit Review Immunology A Study Section, Fall 2006

2007 Michigan Institute for Clinical and Health Research Pilot and

Collaborative Grant Program, University of Michigan, Reviewer

2007 National Institute of Arthritis, Musculoskeletal and Skin Diseases

Special Emphasis Panel ZAR1 MLB-G 01 1, Centers of Research

Translation, May 23-24, 2007

2008 National Institute of Arthritis, Musculoskeletal and Skin Diseases

Special Emphasis Panel ZAR1 MLB-G M1 1, Building Inter-

disciplinary Research Team (BIRT) Revision Awards (R01), June

24-25, 2008

2008 Veterans Administration Career Development (CADE) Study

Section, August 6, 2008, reviewer

2009 National Institute of Arthritis, Musculoskeletal and Skin Diseases

Special Emphasis Panel, ARRA RC1 Challenge Grants, June 5,

2009, primary reviewer

2010 National Institute of Allergy, Immunology, and Infectious Diseases

ZAI1 PA-I (C1), Atopic Dermatits Research Network, February 2,

2010, reviewer

2010 National Institute of Allergy, Immunology, and Infectious Diseases

ZAI1 PA-I (C2), Atopic Dermatits Research Network: Statistical

and Clinical Coordinating Center, February 2, 2010, reviewer

2010 National Institute of Arthritis, Musculoskeletal and Skin Diseases

Special Emphasis Panel, ZAR1 MLB (M1)1, Centers of Research

Translation, November 17-18, 2010, reviewer

2011 National Institute of Arthritis, Musculoskeletal and Skin Diseases

Special Emphasis Panel, ZAR1 HL (M1)1, Skin Diseases Research

Center Grant Review, March 3, 2011, reviewer

James T. Elder, M.D., Ph.D. 4/14/11 4

2011 Centers for Scientific Review, National Institutes of Health,

Cardiovascular and Autoimmune Disease Genetics Study Section,

2011/05 ZRG1 GGG-C (04) M, March 9, 2011, reviewer

GRANT SUPPORT

Recent

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R29-AR40016), TGF- and Tyrosine Kinase Activation

in Psoriasis ; 50% percent effort; role on project: Principal Investigator;

07/01/89-06/30/94 (approximately $70,000 direct costs annually).

Dermatology Foundation Research Grant, Positional Cloning of Epidermal

Differentiation Genes ; role on project: Principal Investigator; 1/1/93-

12/31/93 (approximately $10,000 direct costs annually)

National Institutes of Health, National Center for Human Genome, Research

Genomic Technology/Genetic Disease Pilot/Feasibility Study (P30-

HG00209-03), Directed Linkage Analyses of Familial Psoriasis ; 20%

effort; Francis Collins, PI; role on project: Investigator; 08/01/93-7/31/94

(approximately $20,000 direct costs annually)

Dermatology Foundation Research Grant, Role of Keratinocyte EGF Receptor

Activation in Human Skin Angiogenesis ; role on project: Principal

Investigator / Mentor; 07/01/95-06/30/96 (approximately $10,000 direct

costs)

National Institutes of Health Training Grant (T32AM07197-16), Training Grant

in Cell and Molecular Dermatology ; John Voorhees, PI; role on project:

Preceptor; 07/01/92-06/30/97 (approximately $90,648 direct costs

annually)

Department of Veterans Affairs Merit Review, Expression and Function of

CaN19 in Malignant Progression ; 25 percent effort; role on project:

Principal Investigator; 10/1/94 - 9/30/97 (approximately $92,500 direct

costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR42742-04), Linkage Analysis of Familial

Psoriasis ; 20 percent effort; role on project: Principal Investigator; 3/1/94

- 2/28/98 (approximately $198,200 direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR42742-04S1), Linkage Analysis of Familial

Psoriasis (Supplement); role on project: Principal Investigator; 03/01/97-

02/28/98 ($87,760 direct costs)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR42248-05), Positional Cloning of Epidermal

Differentiation Genes ; 25% effort; role on project: Principal Investigator;

12/01/93-7/31/99 (approximately $544,560 total direct costs)

Dermatology Foundation, EGF Receptor Regulation of Apoptosis in Wound

Healing ; role on project: Principal Investigator / Mentor; 07/01/97 -

06/30/98; ($25,000 direct costs)

Dermatology Foundation, Mapping Locus Control Regions in the Epidermal

Differentiation Complex ; role on project: Principal Investigator / Mentor;

07/01/97 - 06/30/98 ($10,000 direct costs)

University of Michigan Medical School, Clinical Research Partnership Fund,

JNK/TGF- Signaling in Cutaneous Wound Healing ; 5% effort; role on

project: Principal Investigator; 2/1/99 1/31/01 ($50,000 direct costs

annually)

James T. Elder, M.D., Ph.D. 4/14/11 5

National Psoriasis Foundation, Psoriasis Linkage Consortium; role on project:

Investigator; 9/1/98 8/31/00 ($40,000 direct costs)

National Psoriasis Foundation, Molecular Genetics of Familial Psoriasis; role on

project: Principal Investigator; 9/1/00 8/31/01, ($150,000 direct costs)

VA Merit Review (VA #321), CaN19 Function in Regenerative Epidermal

Differentiation ; 25% effort; role on project: Principal Investigator;

4/01/98 09/30/01 ($98,500 direct costs annually)

National Institutes of Health Training Grant (T32-AR017979-25), Training

Grant in Cell and Molecular Dermatology ; John Voorhees, PI; role on

project: Preceptor; 05/01/97 04/30/02 ($112,248 direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR42742); 20% effort; role on project: Principal

Investigator; Linkage Analysis of Familial Psoriasis ; 3/1/98 2/28/03

($272,171 direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR42742 S2), Linkage Analysis of Familial

Psoriasis (Supplement) ; role on project: Principal Investigator; 3/1/98 -

2/28/03 ($175,000 total direct costs)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R21 AR48405-01), Organ Culture of Basal Cell

Carcinoma ; 10% effort; role on project: Principal Investigator; 9/28/01

7/31/03 ($ 50,000 direct costs annually)

National Cancer Institute, National Institutes of Health (P50-CA69568), SPORE

in Prostate Cancer, Kenneth Pienta, PI; role on project, Pilot Project PI,

2/1/03 7/31/03 ($25,000 total direct costs)

VA Merit Review, S100A2 in Oxidative Stress and Carcinogenesis ; 25% effort;

role on project: Principal Investigator; 4/1/02 3/31/05 ($135,000 direct

costs annually)

Dermatology Foundation Research Fellowship, Novel Xenograft Model of

Psoriasis ; 0% effort; role on project: Principal Investigator / Mentor;

07/01/05-06/30/06 ($30,000 direct costs)

American Skin Association, Novel Xenotransplantation Models in Psoriasis ;

0% effort, role on project: Principal Investigator / Mentor; 1/1/06-12/31/06

($15,000 direct costs)

Foundation for the National Institutes of Health; Genetic Association Information

(GAIN) Network, Collaborative Association Study of Psoriasis :

Goncalo Abecasis, PI: Role on project, Co-Investigator; 7/1/06-6/30-07

(approximately $2,000,000 in genotyping services provided and $65,000

in direct costs)

National Institutes of Health Training Grant (T32-AR017979-30), Training

Grant in Cell and Molecular Dermatology ; 5% effort; role on project:

Principal Investigator; 05/01/02 04/30/08 ($148,507 direct costs

annually).

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR42742); Linkage Analysis of Familial Psoriasis ;

15% effort; role on project: Principal Investigator; 4/1/04 9/30/09

($350,000 direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR050511); Identification of Psoriatic Arthritis

Genes in the MHC, James T. Elder, PI; 5% effort; role on project:

Principal Investigator; 4/1/04 9/30/09 ($175,000 direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR054966-02S1); Combined Analysis of Gene

James T. Elder, M.D., Ph.D. 4/14/11 6

Expression and Genetic Variation in Psoriasis (Supplement) ; 0% effort;

role on project: Principal Investigator; 9/1/08 8/31/09 ($50,000 direct

costs)

Dermatology Foundation Research Grant, Biological effects of genetic variation

in the IL 12B and IL23R ; 0% effort; role on project: Mentor. (Johann

Gudjonsson, Principal Investigator); 07/01/08-06/30/09 ($20,000 direct

costs)

National Psoriasis Foundation Research Grant, Phenotype and function of IL-17-

secreting T-cells in psoriasis ; 0% effort, role on project: Mentor. (Allen

Bruce, Principal Investigator); 07/01/08-06/30/09 ($50,000 direct costs

annually)

Current

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR054966); Combined Analysis of Gene Expression

and Genetic Variation in Psoriasis ; 20% effort; role on project: Principal

Investigator; 4/1/07 6/30/12 ($410,320 direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR42742); Linkage Analysis of Familial Psoriasis ;

10% effort; role on project: Principal Investigator; 9/28/09 8/31/14

($440,554 direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR050511); Identification of Psoriatic Arthritis

Genes, James T. Elder, PI; 10% effort; role on project: Principal

Investigator; 9/28/09 7/31/14 ($406,952 direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (RC1AR058315); Genotyping the NPF Biobank for

Psoriasis Susceptibility Genes, James T. Elder, PI; 5% effort, role on

project: Principal Investigator, 9/30/09-8/31/11. ($322,558 direct costs

annually).

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (R01-AR052889); Amphiregulin in Psoriatic Epidermal

Hyperplasia ; 10% effort; role on project: Principal Investigator; 9/15/06

8/31/11 ($186,529 direct costs annually).

National Human Genome Research Institute (U01 HG005924), Design

Approaches for Sequencing Disease-Associated Regions in Psoriasis ; 5%

effort, role on project: Principal Investigator. 10/1/10-9/31/11 ($160,000

in direct costs)

National Institutes of Health Training Grant (T32-AR017979-33), Training

Grant in Cell and Molecular Dermatology ; 5% effort; role on project:

Principal Investigator; 05/01/08 04/30/13 ($168,438 direct costs

annually)

National Institute of Child Health and Development Developmental Biology,

Genetics and Teratology Branch (T32-HD07505), Training Program in

Organogenesis; Deborah Gumucio, PI; role on project: Mentor; 5/01/07

4/30/12 ($308,000 direct costs annually)

National Institutes of General Medical Sciences, National Institutes of Health

(T32-GM07315-31), Graduate Program in Cellular and Molecular

Biology; Jessica Schwartz, PI; role on project: Mentor; 7/1/75 6/30/12

($577,808 direct costs annually)

Dermatology Foundation Physician Scientist Career Development Grant,

Phenotype and function of IL-17-secreting T-cells in psoriasis ; 0%

James T. Elder, M.D., Ph.D. 4/14/11 7

effort, role on project: Mentor. (Allen Bruce, Principal Investigator);

07/01/08-06/30/11 ($55,000 direct costs annually)

Pending

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (1 R01 AR061495-01); Novel Functions of Amphiregulin

in Keratinocyte Growth and Differentiation ; 5% effort; role on project:

Co-Investigator (Stefan Stoll, Principal Investigator); ($250,000 requested

direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (1R01AR062206-01); Functional Genomics of TRAF3IP2

in Psoriasis ; 5% effort; role on project: Principal Investigator; ($250,000

requested direct costs annually)

National Institutes of Health, National Institute for Arthritis, Musculoskeletal and

Skin Diseases (1 R01 AR062382-01); Longitudinal Pharmacogenetic

Analysis of Psoriasis ; 5% effort; role on project: Co-Investigator (Rajan

Nair and Gerald Krueger, Principal Investigators; ($250,000 requested

direct costs annually)

CERTIFICATION AND LICENSURE

1983 Washington Medical Licensure, #252-**-******* (inactive)

1986 Michigan Medical Licensure, #407650

1988 American Board of Dermatology

MILITARY SERVICE

None

HONORS AND AWARDS

1981 Medical Scientist Training Program Award for Outstanding Academic

Achievement

1987 Stelwagon Prize for outstanding resident research, American Academy of

Dermatology

1991 Howard Fox Visiting Professor, New York University Medical Center,

New York, NY

1993 Visiting Professor, 10th Annual Course for Consultants & Registrars,

Brighton, U.K.

1993 Visiting Professor, University of Kiel, Germany.

1995 Visiting Professor, University of Amsterdam, the Netherlands

1995 Visiting Professor, University of Nijmegen, the Netherlands

1998 Louis Forman Visiting Professor, St. John s Institute of Dermatology,

London, UK

1998 Visiting Professor, University of Leicester, UK

1999 Visiting Professor, Case Western Reserve University, Cleveland, OH

2000 Visiting Professor, University of Gothenburg, Sweden

2001 Visiting Professor, University of Cape Town, South Africa

2001 American Dermatological Association

2003- Best Doctors in America

2004 Visiting Professor, Ottawa Dermatologic Society, Ottawa, Canada

2005 Visiting Professor, Canadian Dermatological Association, Quebec

2005 Visiting Professor, Shanghai Dermatological Society, China

2005 Visiting Professor, Chinese Society for Investigative Dermatology, China

James T. Elder, M.D., Ph.D. 4/14/11 8

2006 American Skin Association Award for Outstanding Achievement in

Psoriasis

2007 Visiting Professor, Department of Dermatology, University of Cincinnati,

Cincinnati, OH

2007 Visiting Professor, Department of Dermatology, University of

Pennsylvania, Philadelphia, PA

2008 Kirk D. Wuepper Professor of Medical Genetic Dermatology, University

of Michigan

2008 Visiting Professor, Department of Cellular and Developmental Biology,

Oregon Health Science University, Portland, OR

2009 Eugene Farber Lecturer, Society for Investigative Dermatology, Montreal,

Canada

2010 Fine Lecturer in Dermatology, Emory University, Atlanta, GA

2010 Clinical & Health Services Research Award, University of Michigan

2011 League of Research Excellence, University of Michigan

MEMBERSHIPS AND OFFICES IN PROFESSIONAL SOCIETIES

American Dermatological Association

American Academy of Dermatology

Society for Investigative Dermatology

2006-present Committee on Scientific Programs

2010 Co-Chairman, Committee on Scientific Programs

American Society for Human Genetics

National Psoriasis Foundation,

1999-2002 Medical Advisory Board

2009- Scientific Advisory Committee

Dermatology Foundation

Michigan Dermatological Society

TEACHING ACTIVITIES

National and International

1988-92 Lecture, Mechanisms of Action of Antipsoriatic Drugs, Focus

Session, American Academy of Dermatology

1988 Lecture, Chromatin Structure and Gene Expression in Deletion-

type Hereditary Persistence of Fetal Hemoglobin (HPFH) Insti-

tute of Human Genetics Seminar, University of Minnesota,

Minneapolis

1990 Lecture, Regulation of Epidermal Growth and Gene Expression

by Transforming Growth Factors and Retinoic Acid, INSERM-

U.184/CWRS-LGME, Strasbourg, France.

1990 Lecture, Autocrine and Paracrine Regulation of Keratinocyte

Growth, Cutaneous Biology Research Center, Department of

Dermatology, Harvard Medical School, Massachusetts General

Hospital, Boston

1990 Lecture, Autocrine and Paracrine Regulation of Keratinocyte

Growth, Department of Dermatology Grand Rounds, University

of California at San Francisco

1991 Howard Fox Lecture, Autocrine and Paracrine Regulation of

Keratinocyte Growth, New York University Medical Center, New

York

James T. Elder, M.D., Ph.D. 4/14/11 9

1991 Lecture, Expression of Retinoic Acid Receptors and Binding

Proteins in Human Skin, Department of Dermatology, The

University of Washington, Seattle

1993 Lecture, Psoriasis: Recent Molecular Genetic Clues, 10th

Annual Course for Consultants & Registrars, Brighton, U.K.

1993 Lecture, Molecular Genetics of Psoriasis, University of Kiel,

Kiel, Germany.

1993 Lecture, Basics of Genetic Linkage and Mapping: In Search of

the Psoriasis Gene, Overview of Molecular Biology Course,

American Academy of Dermatology

1994 Peter Horvath Lecture, The Genetics of Psoriasis, DC

Dermatologic Society Meeting, Washington, DC, 1994.

1995 Lecture, EGF receptor activation increases accumulation of

multiple EGF-like growth factors mRNAs by increasing mRNA

stability, Department of Dermatology, Nijmegen University,

Nijmegen, The Netherlands

1995 Keynote lecture, The Genetics of Psoriasis: HLA and Beyond,

Amsterdam Dermatological Society, Department of Dermatology,

University of Amsterdam, Amsterdam, The Netherlands, 1995.

1995 Lecture, The Genetics of Psoriasis: HLA and Beyond,

Department of Immunology, Kiel University, Kiel, Germany

1996 Lecture, Search for Psoriasis Genes: Genetics and Pathobiology,

The Jackson Laboratories, Second Mouse Skin and Hair Mutation

Meeting, Bar Harbor, ME

1996 Lecture, Molecular Genetics: the final answer?, Clinical

Dermatology 2000, Vancouver, Canada

1996 Lecture, The Molecular Genetics of Psoriasis, Clinical

Dermatology 2000, Vancouver, Canada

1997-2000 Lecture, Genetics of Psoriasis, HLA & Beyond, Focus Session,

American Academy of Dermatology

1997 Lecture, Genes and Cutaneous Inflammation - Psoriasis, The

World Congress of Dermatology, Sydney, Australia

1997 Lecture, Antenatal Diagnosis of Lamellar Ichthyoses, The World

Congress of Dermatology, Sydney, Australia.

1997 Lecture, Genetics of Psoriasis, HLA and Beyond ; Chair,

Genetics of Psoriasis Workshop, The World Congress of

Dermatology, Sydney, Australia

1997 Lecture, The Genetics of Psoriasis: HLA and Beyond, Grand

Rounds, Department of Dermatology, University of Cincinnati

1998 Lecture, Psoriasis is a genetic disease - how is it inherited?,

Course on Clinical Disease and its Molecular Basis, American

Academy of Dermatology, Orlando

1998 Louis Forman Lecture, Genetics of Psoriasis: HLA and Beyond,

St. John s Institute of Dermatology, London, UK

1998 Lecture, Early Events in Cutaneous Wound Healing, St. John s

Institute of Dermatology, London, UK

1998 Lecture, Genetics of Psoriasis: HLA and Beyond, Departments

of Dermatology and Genetics, University of Leicester, UK

1999 Audiotape Lecture, Genetics of Psoriasis, Dialogues in

Dermatology, American Academy of Dermatology

1999 Lecture, Signaling Networks Controlling Skin Re-

Epithelialization, Skin Diseases Research Center, Department of

Dermatology, Case Western University, Cleveland

James T. Elder, M.D., Ph.D. 4/14/11 10

1999 Lecture, Role of S100A2 in Keratinocyte Responses to Oxidative

Stress, Department of Pediatrics, University of Zurich,

Switzerland

2000 Ph.D. thesis opponent, for thesis entitled Genetic Susceptibility to

Psoriasis in Sweden, by Fredrik Enlund, Department of Clinical

Genetics, Faculty of Medicine, G teborg University, G teborg,

Sweden

2000 Lecture, The Search for PSORS1, the HLA-linked Genetic

Determinant of Psoriasis Susceptibility, Department of Clinical

Genetics, Sahlgrenska University Hospital, G teborg, Sweden

2001 Lecture, The Genetics of Psoriasis: A Clinician s Perspective,

Texas Dermatological Society Meeting, Houston, TX, May, 2001

2001 Lecture, The Genetics of Psoriasis: HLA and Beyond,

Department of Dermatology, University of Cape Town, South

Africa, August, 2001

2002 Lecture, What s New: Psoriasis, American Dermatological

Association Annual Meeting, Dallas, TX, September 29, 2002

2002 Lecture, Update on Dermatological Disorders: Eczema, Psoriasis,

and Acne, Flower Hospital, Sylvania, OH

2003 Lecture, Genetics of Psoriasis, Focus Session, American

Academy of Dermatology, San Francisco, CA, March 21, 2003

2003 PhD Thesis Opponent (Examiner) for thesis entitled Molecular

Genetics of Psoriasis, by Kati Asumalahti, Department of Human

Genetics, University of Helsinki, Helsinki, Finland

2006 Lecture, Common Dermatological Disorders, Toledo VA

Outpatient Clinic, Toledo, OH, December 6, 2006

2007 Lecture, Genetic Dissection of Psoriasis, Irvin H. Blank

Lecturer, Society for Investigative Dermatology, Los Angeles, CA,

May 9, 2007

2007 Lecture, Psoriasis: From Molecular Biology to Advances in

Therapeutics, Hospital de Clinicas, Montivideo, Uruguay,

September 28, 2007

2007 Lecture, Genetic Dissection of Psoriasis, Department of

Dermatology, University of Cincinnati, Cincinnati, OH October

25, 2007

2007 Lecture, Genetic Dissection of Psoriasis, Department of

Dermatology, University of Pennsylvania, Philadelphia, PA

November 1, 2007

2007 Lecture and Workshop, Genetic Skin Diseases, Society for

Investigative Dermatology, SID Basics of Skin: Pharmaceutics

and Pharmacology Course, Miami, FL, December 6, 2007

2009 Lecture, Molecular Dissection of Psoriasis: Integrating Genetics

and Biology, Baltic Summer School, Kiel, Germany, September

9, 2009

2009 Lecture, Twenty Years of Psoriasis Genetics: The Kiel-Ann

Arbor Connection, Department of Dermatology, Christian-

Albrechts University, Kiel, Germany, September 9, 2009

2010 Lecture, Molecular Dissection of Psoriasis: Genetics Meets

Immunology, Fine Lecture in Dermatology, Emory University,

March 20, 2010

2010 Lecture, Psoriasis: A Tale of Mice and Men, Jackson

Laboratories, Bar Harbor, MI, April 8, 2010

James T. Elder, M.D., Ph.D. 4/14/11 11

2010 Lecture, Molecular Dissection of Psoriasis: Genetics Meets

Immunology, University of Alabama at Birmingham, AL, May

12, 2010

2010 Lecture, Molecular Dissection of Psoriasis: Genetics Meets

Immunology, International Psoriasis Genetics Forum, Chinese

Society for Investigative Dermatology, Guangzhou, China, June

11, 2010

2010 Lecture, "Genetics and Pathogenesis of Psoriatic Arthritis", Second

International Congress on the Spondyloarthropathies, Gent,

Belgium, October 9, 2010

2011 Lecture, Complex Genetic Disorders: Pulling Back the Veil on

Human Disease, All India Institute of Medical Sciences, Delhi,

India, February 25, 2011

University of Michigan

1988 Lecture, Psoriasis, Department of Internal Medicine

1988-92 Lecture, Basics of Molecular Biology, Department of

Dermatology

1988-89 Mentor, Dermatology Resident Research, T Cell Receptor Gene

Rearrangements in Cutaneous T Cell Lymphoma, Vincent C. Ho,

M.D., Trainee.

1989 Lecture, Dermatologic Applications of Molecular Biology,

Michigan Dermatological Society, Ann Arbor, Michigan

1990 Mentor, Medical School Summer Research Project, Familial

Psoriasis, Stacie McMurtry, Trainee

1990-91 Mentor, Dermatology Fellow Research, Molecular Cloning of a

105 Kilodalton Basement Membrane Antigen, Lawrence Chan,

M.D., Trainee

1990 Seminar, The Economy of Keratinocyte Mitogens, Department

of Pathology Research Seminar Series

1991 Lecture, Molecular Genetics of Psoriasis, Michigan Derma-

tological Society Meeting

1991 Seminar, Expression of Retinoic Acid Receptors and Binding

Proteins in Human Skin, Graduate Program in Cellular and

Molecular Biology

1991 Lecture, T-Cell Receptor Gene Rearrangements, Department of

Dermatology

1992 Mentor, Medical Student Summer Research Project, CRABP-II

Responses to Natural and Synthetic Retinoids in Human Skin

Fibroblasts, Alex Kaplan, Trainee

1992-93 Mentor, Dermatology Resident Research, T Cell Cytokine

Expression in Psoriatic Lesions: Heterogeneity and Effects of

Cyclosporin A . Connie Ho, M.D., Trainee

1992 Lecture, DNA Repair: Mechanisms, Molecular and Syndromes,

Department of Dermatology

1992 Lecture, Regulation of Keratinocyte Growth, Department of

Dermatology

1992 Lecture, New Ideas about Old Drugs: Steroids, Retinoids, and

Vitamin D, Michigan Dermatological Society Meeting

1992-93 Lecture Series, Genodermatoses, Department of Dermatology

1993 Mentor, Medical Student Summer Research Project, Expression

of Calcineurin Isoforms in Human Skin, Edsel Kim, Trainee

James T. Elder, M.D., Ph.D. 4/14/11 12

1993 Lecture, Mechanisms of Action of Antipsoriatic Drugs, Senior

Elective Course, Pharmacology and Therapeutics, Department of

Pharmacology

1993 Seminar, Positional Cloning of Epithelial Differentiation Genes,

Division of Nephrology, Department of Internal Medicine

1993 Lecture, Molecular Genetics of Psoriasis, Michigan Derma-

tology Society

1993 Lecture, Mechanisms of Action of Antipsoriatic Drugs, Depart-

ment of Dermatology

1993 Lecture, Papulosquamous Dermatoses, MS III/IV Transitional

Series, Medical School

1993 Lecture, Infectious Skin Diseases, MS III/IV Transitional Series,

Medical School

1993 Lecture, Genetics of HLA-Associated Skin Diseases, Depart-

ment of Dermatology

1994 Lecture, Carcinogenesis, Department of Dermatology

1994 Lecture, Inherited Immunodefeciency Disorders, Department of

Dermatology

1994 Instructor, Live Patient Grand Rounds, Core Curriculum for

Second Year Medical Students

1994 Lecture, Genodermatoses, Core Curriculum for Second Year

Medical Students

1994 Lecture, The Genetics of Psoriasis, Graduate Cellular and

Molecular Biology Symposium

1995 Lecture, DNA Repair in Genodermatoses and Cancer,

Department of Dermatology

1995 Lecture, Bullous Genodermatoses, Department of Dermatology

1995 Lecture, Dermal Genodermatoses, Department of Dermatology

1995 Lecture, Hereditary Immunodeficiency Disorders, Department of

Dermatology

1995 Lecture, Epidermolysis Bullosa: Genetic Insights into Skin

Structure and Function, Core Curriculum for Second Year

Medical Students

1995 Instructor, Live Patient Grand Rounds, Core Curriculum for

Second Year Medical Students

1995 Lecture, Metabolic Disorders, Department of Dermatology

1996 Lecture, How do genetics influence psoriasis?, Michigan

Dermatological Society Meeting

1996 Examiner, Written Preliminary Examination in Pathobiology,

Graduate Program in Cellular and Molecular Biology

1996 Lecture, Introduction to Genodermatoses, Department of Derma-

tology

1996 Lecture, Photocarcinogenesis of Skin, Core Curriculum for

Second Year Medical Students

1996 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

1996 Lecture, Epidermolysis Bullosa: Genetic Insights into Skin

Structure and Function, Core Curriculum for Second Year

Medical Students

1996 Ph.D. Thesis committee, Andrea Lauer, School of Pharmacy

1996 Mentor, Lauren Gold, undergraduate, summer research

1996 Mentor, Annie Hiniker, undergraduate, summer research

James T. Elder, M.D., Ph.D. 4/14/11 13

1996 Oral preliminary examination committee, Yifeng Jia, Graduate

Program in Cellular and Molecular Biology

1997 Oral preliminary examination committee, Yifeng Jia, Graduate

Program in Cellular and Molecular Biology

1997 Lecture, Ichthyoses, Department of Dermatology

1997 Lecture, Acne Management: A Pore Man s Approach,

Department of Pediatrics, St. Joseph Mercy Hospital

1997 Lecture, EGF Receptor Tyrosine Kinase Activation in Cutaneous

Wound Healing, Center for Organogenesis

1997 Lecture, Immunopathogenesis of Psoriasis, Core Curriculum for

Second Year Medical Students

1997 Ph.D. Thesis Committee, Neti Waranuch, School of Pharmacy

1998 Lecture, Mechanisms of Regenerative Hyperplasia, Graduate

Program in Cellular and Molecular Biology Introductory Lecture

Series

1998 Lecture, ErbB Activation: A Critical Early Event in Would

Healing, Cancer Biology Research Seminar, Department of

Radiation Oncology and Comprehensive Cancer Center

1998 Lecture, Ichthyoses, Department of Dermatology

1998 Lecture, Fundamentals of Genetic Linkage, Department of

Dermatology

1998 Mentor, Sherbano Hasan, medical student, summer research

1998 Lecture, Cellular Immunology of the Skin, Core Curriculum for

Second Year Medical Students

1998 Lecture, Cutaneous Manifestations of HIV Infection, Core

Curriculum for Second Year Medical Students

1998 Lecture, Immunopathogenesis of Psoriasis and Atopic

Dermatitis, Core Curriculum for Second Year Medical Students

1998 Lecture, Molecular Mechanisms of Re-Epithelialization,

Graduate Course ACB 681, Organogenesis of a Complex Tissue

1999 Lecture, Postreceptor Signal Transduction Mechanisms in Wound

Healing and Cancer, Cancer Biology Research Seminar,

Department of Radiation Oncology, Comprehensive Cancer Center

1999 Lecture, S100A2 in Oxidative Stress and Carcinogenesis, Cancer

Genetics Research Seminar, Comprehensive Cancer Center

1999 Oral preliminary examination committee, Philip E. Schaner,

Graduate Program in Cellular and Molecular Biology

1999 Lecture, Hereditary Immunodeficiency Disorders, Department of

Dermatology

2000- Lecture, Genetics of Psoriasis, Department of Dermatology

Research Conference

1999 Lecture, Introduction to Immunology, Department of Derma-

tology

1999 Lecture, Cellular Immunology of the Skin, Core Curriculum for

Second Year Medical Students

1999 Lecture, Immunopathogenesis of Psoriasis and Atopic

Dermatitis, Core Curriculum for Second Year Medical Students

2000 Lecture, Signal Transduction Pathways in Cutaneous Wound

Healing, Metastasis / Invasion Workshop, Comprehensive Cancer

Center

2000 Lecture, Molecular Mechanisms of Cutaneous Retinoid

Responsiveness, Department of Pediatrics Research Seminar

James T. Elder, M.D., Ph.D. 4/14/11 14

2000 Lecture, Genetics of Psoriasis, Cancer Biology Research

Seminar, Department of Radiation Oncology and Comprehensive

Cancer Center

2000 Lecture, Fine Mapping of PSORS1, the HLA-linked Component

of Psoriasis Susceptibility, Department of Dermatology

2001- Lecture, Inherited Immunodeficiency Disorders, Department of

Dermatology

2000 Mentor, Ladan Shahabi, medical student, summer research

2000 Lecture, The Search for Psoriasis Genes, Dermatology Sesqui-

centennial Grand Rounds

2000 Lecture, Cellular Immunology of the Skin, Department of

Dermatology

2000 Lecture, Immunopathogenesis of Psoriasis and Atopic

Dermatitis, Department of Dermatology

2000 Lecture, Cellular Immunology of the Skin, Core Curriculum for

Second Year Medical Students

2000 Lecture, Immunopathogenesis of Psoriasis and Atopic

Dermatitis, Core Curriculum for Second Year Medical Students

2000 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

2001 Lecture, Expression and Function of Multiple ErbB Receptors in

Skin, Cancer Biology Research Seminar, Department of

Radiation Oncology and Comprehensive Cancer Center

2001 Lecture, Immunologic Hypersensitivity Reactions, Department

of Dermatology

2001 Lecture, Hereditary Immunodeficiency Disorders, Department of

Dermatology

2001 Lecture, Warts, Department of Dermatology

2001 Ph.D. Thesis Committee, Allison Moffa, Graduate School of

Cellular and Molecular Biology

2001 Lecture, Cellular Immunology of the Skin, Core Curriculum for

Second Year Medical Students

2001 Lecture, Immunopathogenesis of Psoriasis and Atopic

Dermatitis, Core Curriculum for Second Year Medical Students

2001 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

2002 Lecture, Cellular Immunology of the Skin, Department of

Dermatology

2002 Lecture, Hereditary Immunodeficiency Disorder, Department of

Dermatology

2002 Lecture, Genetics of Common Diseases, Department of

Dermatology

2002 Seminar, Molecular Genetics of Melanoma, Department of

Radiation Oncology, Division of Cancer Biology

2002 Lecture, BRAF Mutations in Melanoma, Department of

Dermatology

2002 Lecture, Introduction to Cutaneous Immunology, Department of

Dermatology

2002 Lecture, Cellular Immunology of the Skin, Core Curriculum for

Second Year Medical Students

2002 Lecture, Immunopathogenesis of Psoriasis and Atopic

Dermatitis, Core Curriculum for Second Year Medical Students

2002 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

James T. Elder, M.D., Ph.D. 4/14/11 15

2003 Lecture, Genetics of Psoriasis: The MHC and Beyond,

Department of Human Genetics, University of Michigan

2003 Lecture, Introduction to Immunology, Department of

Dermatology

2003 Lecture, Hereditary Immunodeficiency Disorders . Department of

Dermatology

2003 Lecture, Immunopathogenesis of Psoriasis and Atopic

Dermatitis, Core Curriculum for Second Year Medical Students

2003 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

2004 Lecture, Autocrine Regulation of Keratinocyte Growth by EGF

Receptor Signaling, University of Michigan

2004 Qualifying exam committee chair for Nicole Willmarth, Graduate

Program in Cell and Molecular Biology, University of Michigan.

2004 Qualifying exam committee member for Jaemin Lee, Graduate

Program in Cell and Molecular Biology, University of Michigan.

2004 Thesis committee chairman for Nicole Willmarth, Graduate

Program in Cell and Molecular Biology, University of Michigan.

2004 Lecture, Genetic Analysis of Psoriasis and Psoriatic Arthritis,

Department of Dermatology

2004 Lecture, Immunopathogenesis of Psoriasis and Atopic

Dermatitis, Core Curriculum for Second Year Medical Students

2004 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

2005 Lecture, Management of Common Dermatologic Conditions,

Clinical Pharmacology and Therapeutics Course, Department of

Pharmacology

2005 Lecture, Genetic Skin Disorders, Human Genetics 649,

Advanced Clinical Concepts in Medical Genetics, Department of

Human Genetics

2005 Poster Judge, Graduate Program in Cellular and Molecular

Biology, 25th Annual Symposium and Poster Session

2005 Lecture, Genetic Dissection of PSORS1, Department of

Dermatology

2005 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

2006 Lecture, Genetic Skin Disorders, Human Genetics 649,

Advanced Clinical Concepts in Medical Genetics, Department of

Human Genetics

2006 Lecture, Genodermatoses: Insights into Skin Function, Part I,

Department of Dermatology

2006 Lecture, Genodermatoses: Insights into Skin Function, Part II,

Department of Dermatology

2006 Lecture, Identification of HLA-Cw6 as the Major Genetic

Determinant of Psoriasis Susceptibility, Department of Human

Genetics, University of Michigan

2006 Mentor, Johann Gudjonsson, MD, PhD, Dermatology Resident

2007 Mentor, Allen Bruce, MD, PhD, Dermatology Resident

2007 Lecture, Genetic Skin Disorders, Human Genetics 650,

Advanced Clinical Concepts in Medical Genetics, Department of

Human Genetics

2007 Lecture, Genetics of Psoriasis: An Update, Department of

Dermatology, University of Michigan

James T. Elder, M.D., Ph.D. 4/14/11 16

2007 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

2008 Lecture, Genetic Skin Disorders, Human Genetics 650,

Advanced Clinical Concepts in Medical Genetics, Department of

Human Genetics

2008 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

2009 Lecture, Genetic Skin Disorders, Human Genetics 650,

Advanced Clinical Concepts in Medical Genetics, Department of

Human Genetics

2010 Lecture, "Common Skin Disorders", Dermatology Morning

Conference, July 19, 2010

2010 Kodachromes, "Pemphigus", Resident Book Club, Department of

Dermatology, July 30, 2010

2010 Instructor, Live Patient Grant Grounds, Core Curriculum for

Second Year Medical Students

2011 Lecture, Genetic Skin Disorders, Human Genetics 650,

Advanced Clinical Concepts in Medical Genetics, Department of

Human Genetics

EXTRAMURAL INVITED PRESENTATIONS

Cyclosporine Effects upon TPA-induced ODC Activity and mRNA Levels in

Hairless Mouse Skin, presentation, 2nd International Congress on Cyclosporine,

Washington, D.C., November 1987.

Growth Factors in Psoriasis, presentation, Ps

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