ABDUL R. ABDULLAH, M.D.

**** ********* ******* ****.

Secaucus, NJ, 07094.

Home: 201-***-**** ? Cell: 617-***-**** ? abn0wd@r.postjobfree.com

CLINICAL RESEARCH COLLABORATION

*-****-******* ******* MEDICAL SCHOOL/MASSACHUSETTS GENERAL

HOSPITAL, Boston, MA

Position: Clinical Research Collaborator, Neurology

Key Accomplishments:

. Authored clinical research manuscripts in Neurology

. Mentored clinical research fellows

. Collaborated on clinical studies related to

o Outcomes analyses for the risk of reperfusion

therapies in malignant patients

o Identifying significant opportunities for

intervention for thrombolysis-associated

symptomatic intracerebral hemorrhage

o Devising innovative strategies for the

Massachusetts Department of Public Health to

allow smaller hospitals to achieve primary

stroke center designation

o Safety of early nicotine replacement therapy in

acute stroke patients

CLINICAL RESEARCH EXPERIENCE

1-200*-*-**** FOREST RESEARCH INSTITUTE, Jersey City, NJ

Position: Associate Director, CNS Drug Development

Associate Medical and Safety Director for Schizophrenia

Phase 1 and 2b Trials:

. Safety and Efficacy of RGH-188 in The Acute

Exacerbation of Schizophrenia (MD-16)

. Long-term, Open-label Extension for Safety and

Tolerability of RGH-188 (MD-17)

. Characterization the Dopamine D3 Receptors Occupancy

after Multiple Oral Doses of Cariprazine in Healthy

Male Subjects Using [11C]- -PHNO

Associate Medical and Safety Director for Major Depressive

Disorder Phase 1and 3 Trials:

. Fixed-Dose Study of Escitalopram MR in Adults (SCT-MD-

49)

. Long-term, Open-label Extension Study Of Escitalopram

MR In Adults (SCT-MD-50)

. Fixed-Dose Study of F- 2695 (Levomilnacipran) SR in

Adults (LVM-MD-01)

. Flexible-Dose Study of F2695 SR (LVM-MD-02)

. A Single Dose Pharmacokinetic Study Of F2695 In

Subjects With Normal Or Mild To Severe Impaired Renal

function

Key Accomplishments:

. Track record of quality oriented decisions, and

timely, pragmatic communication across

culturally and geographically diverse teams

. Core team member for medical monitoring and

risk management oversight for trial

execution in Europe, Russia, and South Asia

. Represented the company in medical affairs at

business partner meetings for further

developmental plans for in licensed products

. Medical monitoring and post-marketing

surveillance for large multi-center trials in

US

. Established broad global network in

neuroscience, including KOLs, physicians

and vendors

. Authored and defended clinical protocols at the

protocol review committee meetings

. Made clinical recommendations for FDA

correspondence

. Analyzed, reported and presented safety data

8-200*-**-**** MEMORY PHARMACEUTICALS CORP., Montvale, NJ

Position: Medical Director, Neuropsychiatric Drug

Development

Medical and Safety Director for Alzheimer's Disease and

Schizophrenia Phase 2 Trials:

. Safety and Efficacy of MEM 3454 Versus Placebo in

Patients With Mild to Moderate Alzheimer's Disease

(3454-003)

. Safety and Efficacy of MEM 3454 as Adjunctive

Treatment in Combination With a Preexisting

Antipsychotic in Patients With Cognitive Impairment

Associated With Schizophrenia (CIAS) (3454-101)

. Study of effects of MEM 3454 on Event Related

Potentials in the Brain in Schizophrenia Patients

(3454-102)

. Safety and Efficacy of MEM 1003 Versus Placebo in

Patients With Mild to Moderate Alzheimer's Disease

Key Accomplishments:

. MEM 3454-003 study:

o Finalized data analysis

o Finalized comprehensive clinical study report

o Played a pivotal role in transition activities

that led to Roche opt in for the compound

. Effective management of the CIAS study.

. Evaluated, reported and presented safety data

. Supported business development and scientific affairs

. Acted as a clinical lead with the Roche alliance

POST-DOCTORAL EXPERIENCE

7-200*-*-**** HARVARD MEDICAL SCHOOL/MASSACHUSETTS GENERAL

HOSPITAL, Boston, MA

Positions: Clinical Research Fellow, Neurology, Stroke

Service; Quality Improvement Fellow, Stroke Service

Co-Investigator for Neurology trials, Cardiology Trials and

Registries:

. Department of Public Health, Massachusetts, Paul

Coverdell National Acute Stroke registry for the

Department of Public Health at Massachusetts (Ongoing

Medical Records Auditing for Stroke and TIA Patients,

Management and Execution of the Stroke Collaborative

Reaching for Excellence)

. WEB-THINRR: Web-Enabled Bidirectional Therapeutics

for Human INR Regulation (Project completed)

. DIAS 2 (Desmoteplase in Acute Ischemic Stroke) Trial

. Inter-Rater Reliability of a Simple, Prehospital

Stroke Sign Assessment Tool

. Prediction of Final Infarct Volume by Initial CT

Imaging

. IMS-3 (Interventional Management of Stroke) Trial

. AVAIL (Adherence evaluation after Ischemic Stroke

Longitudinal) Registry

. WATCHMAN Left Atrial Appendage System for Embolic

Protection in Patients with Atrial Fibrillation Trial

. Electrical Impedance Spectroscopy (EIS) for

Monitoring of Neurological Intensive Care Unit (NICU)

Patients with Acute Ischemic and Hemorrhagic Stroke

. SafeFlo 24 Stroke Trial

. STOP AF Trial of Catheter Cryoablation in the

Treatment of Paroxysmal Atrial Fibrillation

Administrative and Committee Responsibilities:

. Partners Neurology Stroke Network, Massachusetts

General Hospital (Associate)

. Get With The Guidelines (GWTG)- Stroke, American

Stroke Association (Protocol design, management and

conduct; assistance to other hospitals for

implementation)

. TeleStroke Center Research, Massachusetts General

Hospital, Clinical Research Committee (Member)

. Acute Stroke Quality Taskforce (ASQT), Massachusetts

General Hospital, Scientific Advisory Committee

(Member)

. Stroke Dashboard Recommendations Board (Consultant)

. Preparing Annual Reports on Quality Indicators for

the Inpatient Care for the Partners HealthCare

CLINICAL EXPERIENCE:

2007-present Cognitive Abilities Screening Instrument (CASI)

Certified

2003-present National Institutes of Health Stroke Scale

(NIHSS) Certified

2003-present Monitoring adverse events for safety of various

drugs and experience with Pharmacovigilance

2003-2007 Six sigma methodologies to improve quality of

care and auditing medical records

2002-2007 Examination of Neurology and Cardiology patients on

regular basis

PREVIOUS RESEARCH EXPERIENCE

2002-2003 BRAIN IMAGING & ANALYSIS CTR, DUKE UNIVERSITY MEDICAL CTR,

Durham, NC

Position: Research Assistant; contributed to the design and

execution of various studies involving stroke

rehabilitation, specifically related to imaging; trained

graduate students in the anatomy of various reflexes

2002-2003 DEPARTMENT OF EXPERIMENTAL CARDIOTHORACIC SURGERY, DUKE

UNIVERSITY

MEDICAL CTR, Durham, NC

Position: Research Apprentice; assisted in experimental

surgery on animal subjects to test grafting of various

materials

2000-2001 DUKE UNIVERSITY EYE CENTER, DUKE UNIVERSITY MEDICAL CTR,

Durham, NC

Position: Research Assistant; performed clinical research

in optical coherence tomography following photodynamic

therapy

1996-1997 ALLAMA IQBAL MEDICAL COLLEGE.

Position: Student Researcher; researched and delivered

presentation on Prolactinomas in males in a physiological

seminar

EDUCATION

ALLAMA IQBAL MEDICAL SCHOOL, Lahore, Pakistan. M.D.,

January 2000

Honors: Class Marshal

Activities: Patient Welfare Society

Fundraising and Blood Donations Committee

Event Planning Advisory Board, Officer

GOVERNMENT COLLEGE LAHORE, Pakistan. F.Sc. Pre-Medical,

September 1993

Honors: summa cum laude

Activities: Old Ravians Society

TEACHING EXPERIENCE

Presentations

2008--2009 Various Operating Committee, Departmental

and the Investigator meetings

2007 New Strategies for Implementation of Guidelines--Lessons Learned from

Six Sigma Methods and Applications. AHA Quality of Care and

Outcomes Collaborative in D.C.

2006 Stroke Conference, Massachusetts General Hospital:

"Hospital Notification by the EMS;" Boston

2006 American Heart Association 7th Quality of Care and Outcomes

conference in Cardiology: "Factors Associated with

Improving Pre-Hospital Code System in Acute Stroke;"

Washington, D.C.

2006 American Heart Association/American Stroke Association

International Stroke Conference:

"Acute Management Oral Abstract;" Kissimmee, FL

2005 Institute of Healthcare Improvement 1st Annual International Summit

on Redesigning Hospital Care: "Implementation of Get With

The Guidelines-Stroke: The MGH experience;" San Diego, CA

Advisory and Supervisory Responsibilities in Clinical or Laboratory Setting

2004-2007 Supervision of Graduate Students/Clinical Research

Fellows/RNs/Coordinators in execution of Clinical Trials,

Health Outcomes research, Patient Medical Record Audits and

Mentoring for new projects. Facilitating various

department operations (Data Management, Biostatistics,

Quality assurance, Audits and Budgeting). Interfacing with

CROs and the Sponsors for Drug/Device Trials.

CERTIFICATION AND COURSEWORK

2006 An Intensive Course on Design and Conduct of Clinical

Trials, MGH, HMS, Boston, MA

2004-2005 Seminars in Problem-Based Biostatistics for Physiologic

Investigators, MGH, HMS, Boston, MA

2004-2005 Basic Biostatistics for Clinical Investigators, MGH, HMS,

Boston, MA

2003-present National Institutes of Health Stroke Scale (NIHSS)

Certified

2003-present Modified Rankin Scale (MRS) Certified

2000-present Pakistan Medical and Dental Council Registration

AWARDS AND HONORS

2006-2007 Conference Sponsorships for Oversight of Clinical Trials

in Cardiology

7/2006 American Heart Association/ American Stroke

Association Appreciation Award for Quality

Improvement in Get With the Guidelines-Stroke (GWTG)

7/2006, 2007 U.S. News & World Reports Recognition of American Heart

Association Performance Achievement Award

2006 The Nathaniel Bowditch Award nomination for Improving Quality of Care

while Reducing Costs, Massachusetts General Hospital Board

of Trustees

2006 Young Investigator Travel Award for the Institute of Healthcare

Improvement

2005 Partners in Excellence Award for outstanding Acute Stroke Care

(TeleStroke Program), Harvard University

2005 Nesson Award for Innovation, Partners Community HealthCare, Inc.

2005 Partners in Excellence Award for Teamwork (Partners Neurology Stroke

Network), Harvard University

PROFESSIONAL AFFILIATIONS

. Ad hoc Reviewer, Stroke Journal, American Heart Association

. Harvard Medical School (HMS) Postdoctoral Association

. Association of Clinical Research Professionals--New England Chapter

. Faculty, American Heart Association/American Stroke Association

. Boston Stroke Society

. Schizophrenia International Research Society, Inc.

BIBLIOGRAPHY

Original Articles

. Abdullah AR, Smith EE, Biddinger PD, Kalenderian D, Schwamm LH.

Advance hospital notification by EMS in acute stroke is associated

with shorter door-to-computed tomography time and increased likelihood

of administration of tissue-plasminogen activator. Prehosp Emerg Care.

2008 Oct-Dec;12(4):426-31.

. Smith EE, Abdullah AR, Petkovska I, Rosenthal E, Koroshetz WJ, Schwamm

LH. Poor outcomes in patients who do not receive intravenous tissue

plasminogen activator because of mild or improving ischemic stroke.

Stroke. 2005;36(11):2497-2499.

. Smith EE, Abdullah AR, Amirfarzan HA, Schwamm LH, Massachusetts

General Hospital, Boston, MA. Serum lipid profile on admission for

ischemic stroke: failure to meet National Cholesterol Education

Program Adult Treatment Panel (NCEP-ATPIII) guidelines. Neurology.

2007 Feb 27;68 (9):660-5.

. Smith EE, Dreyer P, Prvu J, Abdullah AR, Palmeri G, McElligott C,

Schwamm LH. Stroke Center designation can be achieved by small

hospitals: the Massachusetts experience. Crit Pathw Cardiol.2008.

Sep;7(3):173-7.

. Masrur S, Abdullah AR, Smith EE, Hidalgo R, El-Ghandour A, Rordorf G,

Schwamm LH. Risk of Thrombolytic Therapy for Acute Ischemic Stroke in

Patients With Current Malignancy. J Stroke Cerebrovasc Dis. 2010 Jul

1. [Epub ahead of print]

. Goldstein JN, Marrero M, Masrur S, Pervez M, Barrocas AM, Abdullah A,

Oleinik A, Rosand J, Smith EE, Dzik WH, Schwamm LH. Management of

thrombolysis-associated symptomatic intracerebral hemorrhage. Arch

Neurol. 2010 Aug;67(8):965-9.

Reviews/Chapters/Editorials

. Abdullah AR and Schwamm LH. Stroke and TIA. In: Critical Pathways in

Cardiovascular Medicine, edited by Christopher P. Cannon and Patrick

T. O'Gara . Philadelphia (PA): Source: Lippincott Williams & Wilkins

(LWW);2006. p.

. Abdullah AR. Focus on Prehospital Stroke Services: Improving Patient

Care and Outcomes. Applied Neurology Journal (July 2006; Press).

http://appneurology.com/showArticle.jhtml?articleId=191600746

. Eric Smith, Abdullah AR. Clot busters: are some stroke patients

missing out, due to mild symptoms, age? American Heart Association

rapid access journal report (Dallas, Oct.7' 2005; Press)

http://www.americanheart.org/presenter.jhtml?identifier=3034265

Educational Materials

. Schwamm LH, MD, Smith EE, MD, Abdullah AR, MD. Outcomes of Intra-

Arterial Stroke Therapy at MGH. 2004.

. Abdullah AR, MD, Katie Young, MS, Rigotti N, MD, Burgener M, MPH,

Block KR, MD, Schwamm LH, MD . Smoking Cessation for Acute Stroke

Patients 1/1/2003 - 7/1/2005. 2005.

. Abdullah AR. Research Protocol Proposal for a Prospective, Randomized

trial of Safety and Efficacy of Early NRT (Nicotine replacement

therapy) in Active Smokers admitted for Acute Stroke. 2006

Abstracts at Peer Reviewed Meetings

. Mullins ME, Schwamm LH, Maqsood M, Abdullah AR, Gonzalez RG, Koroshetz

WJ, Lev ML. Assessment of the dense vessel sign on noncontrast head CT

II: Evaluation of the hyperdense M2 segment of the MCA by CTA and

introduction of the "MCA dash sign.". American Society of

Neuroradiology. 2004.

. Abdullah AR, Petkovska I, McCarthy C, Smith EE, Schwamm LH. Achieving

Excellence in Stroke Care in the AHA "Get With The Guideline-Stroke"

Pilot Program: Preliminary MGH Experience 2004-2005. Institute of

Healthcare Improvement. Redesigning Hospital Care Summit. (Poster

Presentation). 2005.

. Schwamm LH, Smith EE, Prvu J, Abdullah AR, LaBresh K. Impact of

Admission to a Neurology Service on Outcome and Secondary Stroke

Prevention Strategies. Stroke. 2005.

. Abdullah AR, Schwamm LH, LaBresh KA, Albright D, Frankel MR, Reeves M.

Healthcare Disparities in Acute Intervention for Patients Hospitalized

with Ischemic Stroke or TIA in Get With The Guidelines-Stroke . MGH

Research Symposium (Poster Presentation). 2005.

. Schwamm LH, Smith EE, Abdullah AR, Massachusetts General

Hospital,Boston, MA; Palmeri G, Prvu J, Goyette L, McElligott C,

Dreyer P, Massachusetts Department of Public Health, Boston, MA; on

behalf of the Primary Stroke Service Advisory Committee.

Characteristics Associated with Successful State- Based Licensure for

Acute Stroke Services: The Massachusetts Experience. Stroke. (Poster

Presentation). 2006.

. Smith EE, Abdullah AR, Amirfarzan HA, Schwamm LH, Massachusetts

General Hospital, Boston, MA. Risk Factors For Failure To Control

Hyperlipidemia Prior To Admission For Ischemic Stroke And TIA. Stroke.

2006.

. Abdullah AR, Smith EE, Biddinger P, Kalenderian D, Schwamm LH.

Hospital Notification by EMS in Acute Stroke Is Associated with

Shorter Door-to-CT Time and Increased Likelihood of tPA

Administration. Stroke (Oral Presentation). 2006.

. Abdullah AR, Masrur S, Rivara MB, Cobb NK, El-Ghandour A, Nasir K,

Rigotti NA, Schwamm LH. Safety of Early Nicotine Replacement Therapy

in the Setting of Acute Ischemic Stroke. Stroke. 2007. (Poster

Presentation)

. Masrur S, Abdullah AR, Smith EE, Hidalgo R, El-Ghandour A, Rordorf G,

Schwamm LS. Safety of Thrombolytics in Patients with Acute Ischemic

Stroke. International Stroke Conference, 2008.

. Park S, Masrur S, Abdullah AR, Hidalgo R, El-Ghandour A, Schwamm LS.

Inpatient Acute Ischemic Stroke: Patient Characteristics, Process

Measures and Thrombolytic Rates. International Stroke Conference,

2008.

. Marrero M, Abdullah AR, Barrocas A, Masrur S, Pervez M, Olenik A,

Smith EE, Goldstein JN, Schwamm LH. Emergency Management of

Thrombolysis-Associated Symptomatic Intracerebral Hemorrhage. MGH

Clinical Research Day 2008. (Departmental Award)

. Masrur S, Pervez M, Abdullah AR, El-Ghandour A, Schwamm L. Stroke

Patients Who Pass Initial Dysphagia Screening Are Still At Risk for

Aspiration Pneumonia. International Stroke Conference, 2009.

. Keefe R, Siu C, Fox K, Lowe D, Abdullah AR, Garabaldi G, Santarelli L,

Murray S. Test-retest characteristics of the MATRICS Consensus

Cognitive Battery in a 20-site schizophrenia clinical trial of

R3487/MEM3454 Versus Placebo.

American College of Neuropsychopharmacology, 2009

US Citizen/ Willing to Relocate

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