NADIA IDREES

Address: ***** ********* *****, *** # *, Houston TX 77069

Telephone: 713-***-****

Email: abhzsd@r.postjobfree.com.

Experience

Spring 2013 COMSATS INSTITUTE OF INFORMATION AND TECHNOLOGY

ISLAMABAD.

Worked as an Assistant to Professor

Responsibilities and Obligations Matrix

Research Associate

Member of BRG (Bioinformatics Research Group)

Lab Assistant (BSB)

Preparation of Lecture material and presentations

Checking of Assignments and Quizes

Sept 13- Nov 14 ROOTS MILLENIUM SCHOOL ISLAMABAD

Working in Roots Millenium School as a Teacher of Math, Science, History

Geography

EDUCATION

Bachelors

Spring 2009 – 2013 COMSATS INSTITUTE OF INFORMATION AND TECHNOLOGY

ISLAMABAD.

Bachelors in Bioinformatics (BS)

Calculus and Discrete Mathematics, Statistics

Software Engineering, Artificial Intelligence

Neural Networks, Database and Management Systems

Cell Biology, Bio Chemistry, Introduction to Genomics

Fundamentals of Genetics, Molecular Biology, Developmental Biology

Microbiology and Immunology, Bio Technology

Molecular Genetics, Bio Informatics I/II/III

Essential Techniques in Biochemistry and Molecular Biology

CGPA 3.08

Intermediate

May/June 2007 OPF GIRLS COLLEGE ISLAMABAD F-8/2

HSSC- Pre Medical

Grade A

Matric

March/April 2005 OPF GIRLS COLLEGE ISLAMABAD F-8/2

SSC

Grade A +

References will be furnished upon request .

Skills

Bioinformatics, Genetics, Matlab, DNA sequencing, Genomics, C++, Gel

Electrophoresis, Research, Molecular Biology, Programming, PCR,

Statistics, Microbiology, Science, Biochemistry, Microsoft Word,

PowerPoint, Teaching, Prolog, Python, Java, Databases, Computational

Biology, Data Analysis.

Project

Molecular docking and screening of inhibitor to PBP 3 involved in kidney infections through

Nanobacteria

The study aims to perform molecular docking of primordial penicillin binding protein 3 (PBP 3) of

nanobacteria involved in kidney stones.

Three-dimensional structure of primordial PBP 3 was retrieved from protein data bank (PDB). The 4th

generation derivatives of cephalosporin i.e. cefepime were obtained from ZINC database to dock as

ligands.

Molecular docking of the data set was performed with Autodock Vina with a grid box setting at active

binding site of PBP 3 to target the receptor pocket for binding of ligands. The receptor in PDB format with

partial charges and number of atoms was made compatible with the same pdbqt format of the ligand files

to perform the inhibition of the macromolecule.

The docking results were analyzed in PyMol and 3D Discovery Visualizer. For each docking 20 different

poses were taken out. Model 1 gives out the best possible results. Ligand 460 out of others, defines a very

successful binding energy of -9.0 showing least free energy, hence the most stable complex.

The results indicate that molecular docking of primordial PBP 3 with cefepime, particularly ligand having

ID 460 can be an important event in inhibition of the protein.

Interests

Academia

Managerial affairs

Politics and Current Affairs

Gathering Information Round The Globe

References will be furnished upon request .

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