LU PENG

*** ********* **, ******, ** ***** ab9nmh@r.postjobfree.com 352-***-****

Analytical Chemist

QUALIFICATIONS

Highly-motivated analytical chemist with five years of experience in HPLC and UV-Vis method development and

instrumentation. Demonstrated expertise in analytical techniques including GC, microscopy, FTIR and NMR. Excellent

skills in data processing using MS Excel. Proven track record of maintaining and troubleshooting laboratory

instruments. Effective oral and written communication skills.

SKILLS & EXPERTISE

Separation techniques: HPLC(RP, IEX, SEC, AFC), GC, SDS-PAGE, column chromatography

Spectroscopy: UV/VIS/NIR, fluorescence, FTIR, NMR

Microscopy: optical/fluorescence/confocal microscopy, SEM, TEM

Biomedical techniques: PCR, ELISA, flow cytometry, cell culture/imaging

Chemical synthesis: functional polymer and hydrogel, solid phase synthesis (DNA, RNA, peptide), nanomaterial

synthesis (metallic nanoparticle, quantum dot, carbon nanotube, graphene oxide, micelle), organic synthesis

Material engineering: polymer and hydrogel, functional oligonucleotide, biomolecule conjugation, nanoparticle

engineering, functional nanoporous membrane

5 years of experience in operating, maintaining and troubleshooting laboratory instruments

Consistent productivity with 10+ publications in high-impact peer-reviewed scientific journals and multiple

international conference presentations

PROFESSIONAL EXPERIENCE

Research Assistant Advisor: Dr. Weihong Tan U niversity of Florida

January 2009-present Gainesville, FL

Synthesis and applications of functional phosphoramidites for DNA modification

Synthesized and purified various phosphoramidites containing methacryl, azobenzene and lipid groups

Characterized the phosphoramidites using mass spectrometry and NMR

Incorporated the phosphoramidites into DNA via solid-phase synthesis

Synthesis of biomolecules with different modifiers

Synthesized DNA with different functional groups using an automated DNA synthesizer

Conjugated oligonucleotides and proteins with fluorophors via coupling chemistry

Purified the biomolecular conjugates by HPLC, gel electrophoresis and filtration

Photoresponsive-DNA crosslinked hydrogels with reversible volume change

Synthesized and purified (HPLC) DNA-polymer conjugates

Monitored volume change of hydrogels under UV/Vis light irradiation

Demonstrated the influence of synthetic parameters on volume change

Exonuclease III and graphene oxide based assay for bioanalysis

Designed DNA-based fluorescence assay for bioanalysis

Improved the sensitivity of DNA detection by three orders

Performed analysis of the telomerase activity in extract from as few as 250 cancer cells

Enhanced the sensitivity of mercuy ion detection in solution by 10 times

Intracellular detection using lipid-DNA micelles

Purified lipid-DNA conjugates by HPLC

Synthesized lipid-based DNA micelles by self-assembly of lipid-DNA conjugates

Applied the lipid-based DNA micelles to in vitro sensing of nucleic acids, small molecules and pH

Photo-reversible phase transfer of nanoparticles for catalytic applications

Synthesized and characterized novel azobenzene surfactant and α-cyclodextrin coated gold nanoparticles

Realized photo-reversible phase transfer of nanoparticles between aqueous and organic phases

Applied the phase transfer method to photo-regulation of a catalytic reaction in aqueous phase

Teaching Assistant, Department of Chemistry, University of Florida

September 2008-present Gainesville, FL

Instructed students on basic chemistry experiments and some course materials

Designed and prepared experiments and exams and fulfilled administrative duties for student evaluations

Research Assistant, Dr. Shilin Liu, University of Science and Technology of China

March 2007-June 2008 Hefei, Anhui China

Studied the temperature-induced coil-to-globule phase transition of poly(N-isopropylmethacrylamide)

(PNIPMAM) polymer in aqueous solution using RAMAN spectroscopy

Revealed the effect of structural change of PNIPMAM polymer on hydrogen bonding and hydrophobic

interaction

EDUCATION

University of Florida Gainesville, FL, US

Ph. D. in Analytical Chemistry (Expected in August 2013), Research Advisor: Dr. Weihong Tan

University of Science and Technology of China Hefei, Anhui, China

B. S. in Chemical Physics (2008), Research Advisor: Dr. Shilin Liu

AWARDS

P&G Award for Research Excellence, University of Florida, 2013

Graduate Student Council Travel Award, University of Florida, 2013

College of Liberal Arts and Sciences Travel Award, University of Florida, 2011

Zhang Zongzhi Sci-Tech Scholarship, University of Sci and Tech of China, 2005

Outstanding Freshman Scholarship, University of Sci and Tech of China, 2004

SELECTED PUBLICATIONS

Peng, L.; You, M.; Yuan, Q.; Wu, C.; Han, D.; Chen, Y.; Zhong, Z.; Tan, W. Journal of American Chemical Society,

2012, 134, 123**-*****.

Peng, L.; Zhu, Z.; Chen, Y.; Han, D.; Tan, W. Biosensors and Bioelectronics, 2012, 35, 475– 478.

Peng, L.; Wu, C; You, M; Han, D; Tan, W. Chemical Science, 2013, 4, 1928-1938.

Peng, L.; You, M; Wu, C; Han, D; Öç I.; Chen, T.; Tan, W. Journal of American Chemical Society, under review.

soy,

Han, D.; Zhu, Z.; Wu, C.; Peng, L.; Zhou, L.; Gulbakan, B.; Zhu, G.; Williams, K.; Tan, W. Journal of the American

Chemical Society, 2012, 134, 20797–20804.

Wu, C.; Chen, T.; Han, D.; You, M.; Peng, L.; Cansiz, S.; Zhu, G.; Li, C.; Xiong, X.; Jimenez, E.; Yang. C.J.; Tan,

W. ACS Nano, 2013, 7, 5724–5731.

PRESENTATIONS

Lu Peng, Weihong Tan, “Photo-Reversible Phase Transfer of Nanoparticles with Applications in Catalysis,”

Pittsburgh Conference 2013, Philadelphia, Pennsylvania, March 2013.

Lu Peng, Weihong Tan, “An exonuclease III and graphene oxide-aided assay for DNA detection,” Pittsburgh

Conference 2011, Atlanta, Georgia, March 2011

Lu Peng, Weihong Tan, “Telomerase detection in cell lysates using exonuclease III induced target recycling,”

NanoFlorida 2011, Miami, Florida, September 2011

Lu Peng, Weihong Tan, “A Light-Powered Dynamic Hydrogel based on Reversible DNA Hybridization.”

Pittsburgh Conference 2012, Orlando, Florida, March 2012

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