Ritu Kumari Research Associate

Ph.D Department of Medical Genetics

Sanjay Gandhi Post Graduate,

Institute of Medical Sciences,

C- Block, Lucknow-226014.

Email- ab8sh9@r.postjobfree.com

ab8sh9@r.postjobfree.com

Nationality- Indian.

Current Position: working as a Research Associate, in Department of Medical Genetics,

SGPGIMS, Lucknow

ACADEMIC QUALIFICATIONS:

B.Sc. (Zoology, Botany and Chemistry) from CSJM University Kanpur, India

M.Sc (Life Sciences) K. N. Kaul. Institute of Life Sciences, Kanpur University, U.P India

PhD: Awarded in June 2013, topic entitled as “Association of sodium ion channel and

GABA receptor gene polymorphisms in epilepsy susceptibility and pharmacotherapy ”

under supervision of Dr. R.K. Garg, Prof. and Head, Department of Neurology, King George

Medical University (KGMU), Lucknow, India.

PUBLICATIONS:

1. R. Kumari, Ram Lakhan, Surendra kumar, R.K.Garg, UK Mishra, J.Kalita, B. Mittal.

SCN1AIVS5-91G>A polymorphism is associated with susceptibility to epilepsy but not

with drug responsiveness. Biochimie 95-201*-****-****.

2. Kumari R, Lakhan R, Kalita J, Misra UK, Mittal B. Association of alpha subunit of

GABAA receptor subtype gene polymorphisms with epilepsy susceptibility and drug

resistance in north Indian population. Seizure. 2010 ;( 19):237-41.

3. Kumari R, Lakhan R, Kalita J, Garg R.K. Misra UK, Mittal B. Potential role of

GABAA receptor subunit; GABRA6, GABRB2 and GABRR2 gene polymorphisms in

epilepsy susceptibility and pharmacotherapy in North Indian population. Clinica

Chimica Acta 2011; ( 412):1244-1248.

4. Kumari R, Lakhan R, Garg RK, Kalita J, Misra UK, Mittal B. Pharmacogenomic

association study on the role of drug metabolizing, drug transporters and drug target gene

polymorphisms in drug-resistant epilepsy in a north Indian population. Indian Journal of

Human Genetics 2011; Volume 17 Supplement 1.

5. Lakhan R, Kumari R, Misra UK, Kalita J, Pradhan S. & Mittal B. Differential Role of

Sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple

drug resistance in north Indian population. Brit J Clin Pharmacol. 2009b;(68):214-220

6. Lakhan, R., Kalita, J., Misra, U.K., Kumari, R. & Mittal, B. (2009) Association of

intronic polymorphism rs3773364 A>G in synapsin-2 gene with idiopathic epilepsy.

Synapse, 2009; 64, 403-408.

7. Lakhan R, Kumari R, Singh K, Misra UK, Kalita J, Mittal B, Possible role of CYP2C9

and CYP2C19 single nucleotide polymorphisms in drug refractory Epilepsy. Indian J

Med Res 134, September 2011, pp 295-301.

BOOK CHAPTER:

Balraj Mittal, Ritu Kumari, Ram Lakhan, R.K. Garg, J. Kalita, U.K. Misra (2012).

Pharmacogenomics of Antiepileptic Drug Therapy”. In: Seizures and Anti-Epileptic

Drugs (ISBN: 978-1-62100-255-0), Eds. Willard Hosten and Aleph Burtsev. Nova

Science Publisher, NY, USA PP. 113-132

Technique Proficient in:

Isolation of, DNA, RNA from cells and tissues

Agarose gel, PAGE and SDS- PAGE

Multiplex PCR, RT-PCR

Single Stranded Conformational Polymorphism (SSCP)

Restriction Fragment length polymorphism (RFLP)

High performance Liquid chromatography (HPLC)

Western Blotting, ELISA

Cell culture

Basic knowledge of cytogenetic

Clinical Data Management

Mice work handling

Theoretical:

Attended regular academic sessions comprising of journal clubs, seminars and research forums

on current and advanced topics of immunology and genetics. Regularly presented semina rs,

journal clubs, journal reviews in the aforesaid sessions

AWARDS:

Women Scientist Award from Department of Science and Technology, New Delhi

(2006-2009)

Senior Research Fellowship, Indian Council of Medical Research, New Delhi, (2009-

2013

COURSES AND WORKSHOPS ATTENDED:

1. An introduction to the role of bioinformatics in translational medicine Research cell,

nd rd

KGMU, Lucknow (India) 22 & 23 July, 2010

2. Protein structure prediction biomedical informatics centre school of telemedicine &

Biomedical informatics SGPGIMS, Lucknow. December 19-20, 2008

3. Department of Radiotherapy, KGMU, Lucknow. International symposium on prognostic

th th

& predictive factors in cancer management 15 -16 December, 2008

4. Midterm conference of the Indian society of gastroenterology Ist-2nd September, 2007,

SGPGIMS, Lucknow

ABSTRACTS AND POSTER PRESENTATION:

1. Ritu Kumari, R.K.Garg, Ram Lakhan, UK Misra, J Kalita, B Mittal "Role of genetic

variants of GABAA receptor subunit genes in epilepsy susceptibility and drug resistance

in north India,” .Accepted for international conference Society Neuroscience, November

12-16,2011. Poster in Session; Epilepsy Inhibition: (T2 249.08).

2. Ritu Kumari, R.K.Garg, Ram Lakhan, UK Misra, J Kalita, S Pradhan, MK Singh, B

Mittal. Pharmacogenomic Study of Drug Transporter ABCB1 and Drug Target SCN1A

in Epilepsy Patients from North India. Poster 365, HUGO's 13th Human Genome

Meeting Hyderabad, 27- 30 Sep, 2009 India.

.

3. Ritu Kumari, Lakhan R, R.K.Garg, UK, UK Misra, J Kalita, B Mittal Association of

GABA receptor gene polymorphisms in epilepsy susceptibility and drug resistance in

North Indian epilepsy patient (ISHG 2010, P 39) SGPGIMS, Lucknow.

4. Balraj Mittal, Ritu Kumari, Lakhan R, R.K.Garg, U.K. Misra. Influence of SCN1A,

SCN2A and SYN2 Gene Polymorphism in Epilepsy Susceptibility And Therapeutic

Efficacy. ESHG Vienna May 2009.

5. Balraj Mittal, Ritu Kumari, Lakhan R, R.K.Garg, J Kalita, UK Misra. Differential Role

of Pharmacogenetic Markers in Epilepsy Susceptibility and Therapeutic Response.

Abstract 6 (ISHG 2009, P 37) New Delhi India.

6. Surendra kumar, Ritu Kumari, Garg. R.K., Misra UK, Kalita J. Influence of SCN1A

IVS5 – 91 G>A (rs 3812718) gene polymorphism with epilepsy susceptibility and

pharmacotherapy in North Indian population. ISHG 2012) Chandigarh, India.

COMPUTER

I am well aware with Windows and Mac OS: MS-Office (Word, Excel, Power point) &

Internet Explorer. Statistical Software: SPSS, Prism and Excel, Photo-editing Software:

Office picture manager, Scientific Software: Epi-info, Quanto, Laser-gene DNA-Star-7

Basic Bioinformatics, Primer Designing, Basic Alignment tools (Protein, DNA)

REFEREES:

1. Dr. R K Garg (PhD. Guide)

Professor and Head

Department of Neurology

King George's Medical University

Ph: 4003496 (R), Mobile: 933-***-****.

E-mail: ab8sh9@r.postjobfree.com,Lucknow, 226003 [INDIA]

2. Dr. Balraj Mittal

Professor

Department of Genetics,

SGPGIMS

Raebareli Road, Lucknow- 14 [INDIA]

E Mail: ab8sh9@r.postjobfree.com, ab8sh9@r.postjobfree.com

Mobile: 983-***-****

Phone- 0522- 266****-*** Extn: 4322

3. Prof. U.K. Misra

Professor & Head

Department Of Neurology

Sanjay Gandhi Post Graduate Institute of Medical Sciences

Raebareli Road, Lucknow-14 [INDIA]

E Mail- ab8sh9@r.postjobfree.com, ab8sh9@r.postjobfree.com Phone- 052*-*******

PERMANENT ADDRESS: RITU KUMARI

C/o Mr. R.P.Shah

85/58 Sugar mill bunglow.

No-12C, Cooperganj

Kanpur, 208003 U.P (INDIA).

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